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amn-1 Protein amnionless [ Caenorhabditis elegans ]

Gene ID: 190697, updated on 2-Nov-2024

Summary

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Official Symbol
amn-1
Official Full Name
Protein amnionless
Primary source
WormBase:WBGene00022285
Locus tag
CELE_Y75B7AL.2
See related
AllianceGenome:WB:WBGene00022285
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein localization and receptor-mediated endocytosis. Predicted to be located in plasma membrane. Predicted to be active in apical plasma membrane and endocytic vesicle. Human ortholog(s) of this gene implicated in megaloblastic anemia. Orthologous to human AMN (amnion associated transmembrane protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See amn-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (1332276..1358151, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Homolog of Odr-2 (Two) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene C2 domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increasing Complexity of the N-Glycome During Caenorhabditis Development. Wilson IBH, et al. Mol Cell Proteomics, 2023 Mar. PMID 36717059, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in receptor-mediated endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein amnionless
NP_001300287.1
  • Confirmed by transcript evidence
NP_503404.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    1332276..1358151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071003.6 → NP_503404.3  Protein amnionless [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503404.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q965S7
    Conserved Domains (1) summary
    pfam14828
    Location:25 → 268
    Amnionless; Amnionless

  2. NM_001313358.4 → NP_001300287.1  Protein amnionless [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3ASJ2
    Conserved Domains (1) summary
    pfam14828
    Location:2 → 101
    Amnionless; Amnionless
Nucleotide Protein
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