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spe-19 CX domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 190958, updated on 2-Nov-2024

Summary

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Official Symbol
spe-19
Official Full Name
CX domain-containing protein
Primary source
WormBase:WBGene00013747
Locus tag
CELE_Y113G7A.10
See related
AllianceGenome:WB:WBGene00013747
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in spermatid development. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See spe-19 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (20040949..20047410, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ligand-Gated ion Channel Neighboring gene ncRNA Neighboring gene Ashwin Neighboring gene pseudo Neighboring gene Serpentine Receptor, class H Neighboring gene Homeobox protein ttx-1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SPE-8, a protein-tyrosine kinase, localizes to the spermatid cell membrane through interaction with other members of the SPE-8 group spermatid activation signaling pathway in C. elegans. Muhlrad PJ, et al. BMC Genet, 2014 Jul 14. PMID 25022984, Free PMC Article
  2. Spatial Transcriptomics of Nematodes Identifies Sperm Cells as a Source of Genomic Novelty and Rapid Evolution. Rödelsperger C, et al. Mol Biol Evol, 2021 Jan 4. PMID 32785688, Free PMC Article
  3. The genetic and molecular analysis of spe-19, a gene required for sperm activation in Caenorhabditis elegans. Geldziler B, et al. Dev Biol, 2005 Jul 15. PMID 15939418
  4. Caenorhabditis elegans sperm membrane protein interactome. Marcello MR, et al. Biol Reprod, 2018 Jun 1. PMID 29546388, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SPE-19 is a candidate for the receptor/co-receptor necessary for the transduction of the activation signal across the sperm plasma membrane.
    Title: The genetic and molecular analysis of spe-19, a gene required for sperm activation in Caenorhabditis elegans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in spermatid development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CX domain-containing protein
NP_507871.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20040949..20047410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075470.5 → NP_507871.3  CX domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507871.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2Y6
Nucleotide Protein
Heading Accession and Version

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