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Y119D3B.14 Tr-type G domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 191043, updated on 2-Nov-2024

Summary

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Official Symbol
Y119D3B.14
Official Full Name
Tr-type G domain-containing protein
Primary source
WormBase:WBGene00022491
Locus tag
CELE_Y119D3B.14
See related
AllianceGenome:WB:WBGene00022491
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Is expressed in intestine. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Orthologous to human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y119D3B.14 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (1185248..1193812, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cadherin domain-containing protein Neighboring gene ncRNA Neighboring gene Enhancer of AKt-1 null Neighboring gene DUF19 domain-containing protein Neighboring gene putative 26S proteasome complex subunit dss-1 Neighboring gene Large ribosomal subunit protein mL45

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome disassembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tr-type G domain-containing protein
NP_497345.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    1185248..1193812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064944.7 → NP_497345.2  Tr-type G domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497345.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    D4AFK0, Q95Y73
    Conserved Domains (1) summary
    COG0480
    Location:23 → 727
    FusA; Translation elongation factor EF-G, a GTPase [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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