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ZK354.8 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

Gene ID: 191295, updated on 2-Nov-2024

Summary

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Official Symbol
ZK354.8
Official Full Name
Protein-tyrosine phosphatase
Primary source
WormBase:WBGene00022709
Locus tag
CELE_ZK354.8
See related
AllianceGenome:WB:WBGene00022709
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Orthologous to human PTPN9 (protein tyrosine phosphatase non-receptor type 9). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ZK354.8 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (5303988..5306140, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene pseudo Neighboring gene Serine/threonine-protein phosphatase Neighboring gene MSP domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein-tyrosine phosphatase
NP_500775.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    5303988..5306140 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068374.5 → NP_500775.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500775.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91568
    Conserved Domains (2) summary
    smart00194
    Location:200 → 451
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:225 → 451
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
Nucleotide Protein
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