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tmem-17 uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 191316, updated on 2-Nov-2024

Summary

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Official Symbol
tmem-17
Official Full Name
uncharacterized protein
Primary source
WormBase:WBGene00022733
Locus tag
CELE_ZK418.3
See related
AllianceGenome:WB:WBGene00022733
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in non-motile cilium assembly. Located in ciliary transition zone. Is expressed in ciliated neurons. Orthologous to human TMEM17 (transmembrane protein 17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tmem-17 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (7070281..7070885)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Ubiquitin-conjugating enzyme E2 ubc-18 Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene BOS complex subunit TMEM147

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone. Roberson EC, et al. J Cell Biol, 2015 Apr 13. PMID 25869670, Free PMC Article
  2. MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. Li C, et al. PLoS Biol, 2016 Mar. PMID 26982032, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in non-motile cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in ciliary transition zone IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary transition zone IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_498542.2
  • Product from WormBase gene class tmem;
    Confirmed by transcript evidence; TMEM (human TransMEMbrane protein) homolog

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7070281..7070885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066141.2 → NP_498542.2  uncharacterized protein CELE_ZK418.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498542.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23481
    Conserved Domains (1) summary
    pfam09799
    Location:1 → 95
    Transmemb_17; Predicted membrane protein
Nucleotide Protein
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