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tba-8 Tubulin alpha-8 chain [ Caenorhabditis elegans ]

Gene ID: 191455, updated on 2-Nov-2024

Summary

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Official Symbol
tba-8
Official Full Name
Tubulin alpha-8 chain
Primary source
WormBase:WBGene00006534
Locus tag
CELE_ZK899.4
See related
AllianceGenome:WB:WBGene00006534
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in germ line; posterior lateral ganglion; retrovesicular ganglion; seam cell; and ventral cord neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tba-8 in Genome Data Viewer
Location:
chromosome: X
Exon count:
12
Sequence:
Chromosome: X; NC_003284.9 (9455485..9458348, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Acyltransferase 3 domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene C2H2-type domain-containing protein Neighboring gene C2H2-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microtubule plus-end dynamics link wound repair to the innate immune response. Taffoni C, et al. Elife, 2020 Jan 29. PMID 31995031, Free PMC Article
  2. Global Proteomic Response of Caenorhabditis elegans Against PemK(Sa) Toxin. Mir DA, et al. Front Cell Infect Microbiol, 2019. PMID 31214513, Free PMC Article
  3. In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics. Lacroix B, et al. Dev Cell, 2014 Apr 28. PMID 24780738, Free PMC Article
  4. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
  5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tubulin alpha-8 chain
NP_509591.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    9455485..9458348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077190.5 → NP_509591.2  Tubulin alpha-8 chain [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509591.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P52274
    Conserved Domains (2) summary
    PTZ00335
    Location:6 → 451
    PTZ00335; tubulin alpha chain; Provisional
    cd02186
    Location:6 → 438
    alpha_tubulin; The alpha-tubulin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P52274.2

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