U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

htas-1 Histone H2A [ Caenorhabditis elegans ]

Gene ID: 191549, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
htas-1
Official Full Name
Histone H2A
Primary source
WormBase:WBGene00014240
Locus tag
CELE_ZK1251.1
See related
AllianceGenome:WB:WBGene00014240
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of chromatin. Predicted to be involved in heterochromatin formation. Predicted to be located in chromosome. Predicted to be part of nucleosome. Predicted to be active in nucleus. Is expressed in sperm and spermatid. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See htas-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_003282.8 (9682984..9683533, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Insulin-like peptide 7;putative insulin-like peptide beta-type 4 Neighboring gene ncRNA Neighboring gene 3-oxo-5-alpha-steroid 4-dehydrogenase Neighboring gene pseudo

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Nematode histone H2A variant evolution reveals diverse histories of retention and loss and evidence for conserved core-like variant histone genes. Singh S, et al. PLoS One, 2024. PMID 38814971, Free PMC Article
  2. The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. elegans. Samson M, et al. PLoS Genet, 2014 Oct. PMID 25299455, Free PMC Article
  3. Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans. Murphy CT, et al. Proc Natl Acad Sci U S A, 2007 Nov 27. PMID 18025456, Free PMC Article
  4. Gamma radiation induces life stage-dependent reprotoxicity in Caenorhabditis elegans via impairment of spermatogenesis. Maremonti E, et al. Sci Total Environ, 2019 Dec 10. PMID 31425988
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The histone H2A variant HTAS-1 exclusively marks paternal chromatin.
    Title: The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. elegans.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
part_of nucleosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Histone H2A
NP_501718.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9682984..9683533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069317.2 → NP_501718.1  Histone H2A [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501718.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23429
    Conserved Domains (2) summary
    smart00414
    Location:29 → 132
    H2A; Histone 2A
    cd00074
    Location:27 → 132
    H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.