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his-1 Histone H4 [ Caenorhabditis elegans ]

Gene ID: 191667, updated on 2-Nov-2024

Summary

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Official Symbol
his-1
Official Full Name
Histone H4
Primary source
WormBase:WBGene00001875
Locus tag
CELE_T10C6.14
See related
AllianceGenome:WB:WBGene00001875
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Orthologous to several human genes including H4C1 (H4 clustered histone 1); H4C11 (H4 clustered histone 11); and H4C12 (H4 clustered histone 12). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See his-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_003283.11 (16042520..16042831)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Histone H2A Neighboring gene Histone H3 Neighboring gene ncRNA Neighboring gene F-box domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleotide sequences of Caenorhabditis elegans core histone genes. Genes for different histone classes share common flanking sequence elements. Roberts SB, et al. J Mol Biol, 1989 Apr 20. PMID 2544730
  2. The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division. Pettitt J, et al. J Cell Sci, 2002 Feb 15. PMID 11865041
  3. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
  4. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article
  5. Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation. Baytek G, et al. Biotechniques, 2022 May. PMID 35297663

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in nucleosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Histone H4
NP_507034.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    16042520..16042831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074633.3 → NP_507034.1  Histone H4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507034.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02619, P62784, Q7JNV2
    Conserved Domains (1) summary
    PLN00035
    Location:1 → 103
    PLN00035; histone H4; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62784.2

Gene LinkOut

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