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his-6 Histone H3 [ Caenorhabditis elegans ]

Gene ID: 191668, updated on 2-Nov-2024

Summary

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Official Symbol
his-6
Official Full Name
Histone H3
Primary source
WormBase:WBGene00001880
Locus tag
CELE_F45F2.13
See related
AllianceGenome:WB:WBGene00001880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Orthologous to several human genes including H3C1 (H3 clustered histone 1); H3C10 (H3 clustered histone 10); and H3C11 (H3 clustered histone 11). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See his-6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_003283.11 (8534567..8534977, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Histone H2B 2 Neighboring gene ncRNA Neighboring gene Histone H2A Neighboring gene Histone H4 Neighboring gene Histone H2A/H2B/H3 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Sural S, et al. Sci Adv, 2020 Oct. PMID 33087356, Free PMC Article
  2. The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division. Pettitt J, et al. J Cell Sci, 2002 Feb 15. PMID 11865041
  3. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Histone H3
NP_505199.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8534567..8534977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072798.3 → NP_505199.1  Histone H3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505199.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08898, Q9TW44
    UniProtKB/TrEMBL
    K7ZUH9
    Conserved Domains (1) summary
    PTZ00018
    Location:1 → 136
    PTZ00018; histone H3; Provisional
Nucleotide Protein
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Gene LinkOut

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