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his-34 Histone H2B 1 [ Caenorhabditis elegans ]

Gene ID: 191679, updated on 2-Nov-2024

Summary

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Official Symbol
his-34
Official Full Name
Histone H2B 1
Primary source
WormBase:WBGene00001908
Locus tag
CELE_F17E9.9
See related
AllianceGenome:WB:WBGene00001908
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Orthologous to several human genes including H2BC1 (H2B clustered histone 1); H2BC12 (H2B clustered histone 12); and H2BC17 (H2B clustered histone 17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See his-34 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_003282.8 (8335972..8336340)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Histone H3 Neighboring gene Histone H2A Neighboring gene pseudo Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evidence for dynamic alteration in histone gene clusters of Caenorhabditis elegans: a topoisomerase II connection? Holt SJ, et al. Genet Res, 2002 Feb. PMID 11974600
  2. Structural Insights into ceNAP1 Chaperoning Activity toward ceH2A-H2B. Liu Y, et al. Structure, 2019 Dec 3. PMID 31653339
  3. The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division. Pettitt J, et al. J Cell Sci, 2002 Feb 15. PMID 11865041
  4. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in innate immune response IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Histone H2B 1
NP_501409.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    8335972..8336340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069008.1 → NP_501409.1  Histone H2B 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501409.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02656, P04255
    Conserved Domains (1) summary
    smart00427
    Location:24 → 120
    H2B; Histone H2B
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P04255.4

Gene LinkOut

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