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snf-10 Transporter [ Caenorhabditis elegans ]

Gene ID: 191769, updated on 2-Nov-2024

Summary

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Official Symbol
snf-10
Official Full Name
Transporter
Primary source
WormBase:WBGene00004909
Locus tag
CELE_Y32F6A.2
See related
AllianceGenome:WB:WBGene00004909
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable L-amino acid transmembrane transporter activity and amino acid:sodium symporter activity. Involved in positive regulation of amoeboid sperm motility. Located in cell body membrane. Is expressed in germ line; sperm; spermatid; and spermatocyte. Orthologous to human SLC6A7 (solute carrier family 6 member 7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See snf-10 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (10438330..10440823, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Amino acid transporter transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene SET domain-containing protein Neighboring gene Poly(A) polymerase Neighboring gene Retinoid-inducible serine carboxypeptidase Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SLC6 family transporter SNF-10 is required for protease-mediated activation of sperm motility in C. elegans. Fenker KE, et al. Dev Biol, 2014 Sep 1. PMID 24929237, Free PMC Article
  2. SNF-10 connects male-derived signals to the onset of sperm motility in C. elegans. Fenker KE, et al. Worm, 2015 Jan-Mar. PMID 26430556, Free PMC Article
  3. Zinc is an intracellular signal during sperm activation in Caenorhabditis elegans. Tan CH, et al. Development, 2021 Nov 1. PMID 34739028, Free PMC Article
  4. An RNAi screen identifies genes that regulate GABA synapses. Vashlishan AB, et al. Neuron, 2008 May 8. PMID 18466746
  5. A database of Caenorhabditis elegans behavioral phenotypes. Yemini E, et al. Nat Methods, 2013 Sep. PMID 23852451, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables amino acid:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in gamma-aminobutyric acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in glycine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of amoeboid sperm motility IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cell body membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Transporter
NP_505682.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10438330..10440823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073281.4 → NP_505682.2  Transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505682.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45915
    Conserved Domains (1) summary
    cl11976
    Location:78 → 628
    SNF; Sodium:neurotransmitter symporter family
Nucleotide Protein
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