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sra-6 Serpentine receptor class alpha-6 [ Caenorhabditis elegans ]

Gene ID: 191777, updated on 2-Nov-2024

Summary

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Official Symbol
sra-6
Official Full Name
Serpentine receptor class alpha-6
Primary source
WormBase:WBGene00005032
Locus tag
CELE_AH6.10
See related
AllianceGenome:WB:WBGene00005032
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Located in cilium. Is expressed in head; intestine; nervous system; tail; and in male. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sra-6 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (9548405..9550818, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class alpha-7 Neighboring gene pseudo Neighboring gene Neuropeptide-Like Protein Neighboring gene Secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The C. elegans homeodomain gene unc-42 regulates chemosensory and glutamate receptor expression. Baran R, et al. Development, 1999 May. PMID 10207148
  2. HLH-14 is a C. elegans achaete-scute protein that promotes neurogenesis through asymmetric cell division. Frank CA, et al. Development, 2003 Dec. PMID 14627726
  3. The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in Caenorhabditis elegans. Fujiwara M, et al. Genetics, 2015 Dec. PMID 26434723, Free PMC Article
  4. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Liedtke W, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14581619, Free PMC Article
  5. A Memory Circuit for Coping with Impending Adversity. Eliezer Y, et al. Curr Biol, 2019 May 20. PMID 31056393, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of chemical stimulus IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cilium IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Serpentine receptor class alpha-6
NP_496052.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9548405..9550818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063651.2 → NP_496052.1  Serpentine receptor class alpha-6 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496052.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09208
    Conserved Domains (1) summary
    pfam02117
    Location:1 → 328
    7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09208.1

Gene LinkOut

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