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tsp-3 Tetraspanin [ Caenorhabditis elegans ]

Gene ID: 192059, updated on 2-Nov-2024

Summary

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Official Symbol
tsp-3
Official Full Name
Tetraspanin
Primary source
WormBase:WBGene00006629
Locus tag
CELE_Y39E4B.4
See related
AllianceGenome:WB:WBGene00006629
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tsp-3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (13212666..13214463)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Polypeptide N-acetylgalactosaminyltransferase 5 Neighboring gene UDG domain-containing protein Neighboring gene Leishmanolysin-like peptidase Neighboring gene tRNA-Tyr Neighboring gene ncRNA Neighboring gene tRNA-Asn Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity. Sutphin GL, et al. Aging Cell, 2017 Aug. PMID 28401650, Free PMC Article
  2. Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids. Möller S, et al. Aging (Albany NY), 2020 Jul 7. PMID 32634117, Free PMC Article
  3. Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans. Lewis JA, et al. BMC Genomics, 2009 Apr 29. PMID 19402892, Free PMC Article
  4. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Tetraspanin
NP_499724.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    13212666..13214463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067323.3 → NP_499724.1  Tetraspanin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499724.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2K6
    Conserved Domains (1) summary
    pfam00335
    Location:9 → 208
    Tetraspannin; Tetraspanin family
Nucleotide Protein
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