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tsp-7 Tetraspanin [ Caenorhabditis elegans ]

Gene ID: 192062, updated on 2-Nov-2024

Summary

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Official Symbol
tsp-7
Official Full Name
Tetraspanin
Primary source
WormBase:WBGene00006633
Locus tag
CELE_T23D8.2
See related
AllianceGenome:WB:WBGene00006633
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in DA neuron; head neurons; tail neurons; touch receptor neurons; and ventral cord neurons. Orthologous to human CD63 (CD63 molecule). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tsp-7 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (9969972..9973177, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase Neighboring gene ncRNA Neighboring gene Protein mom-5 Neighboring gene Protein LTV1 homolog Neighboring gene Eukaryotic translation initiation factor 3 subunit C

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species. Bubier JA, et al. PLoS One, 2019. PMID 30978202, Free PMC Article
  2. Ectocytosis prevents accumulation of ciliary cargo in C. elegans sensory neurons. Razzauti A, et al. Elife, 2021 Sep 17. PMID 34533135, Free PMC Article
  3. Cilia-Derived Extracellular Vesicles in Caenorhabditis Elegans: In Vivo Imaging and Quantification of Extracellular Vesicle Release and Capture. Razzauti A, et al. Methods Mol Biol, 2023. PMID 37140803
  4. A gene expression fingerprint of C. elegans embryonic motor neurons. Fox RM, et al. BMC Genomics, 2005 Mar 21. PMID 15780142, Free PMC Article
  5. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Tetraspanin
NP_492636.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    9969972..9973177 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060235.2 → NP_492636.1  Tetraspanin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492636.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XVI4
    Conserved Domains (2) summary
    cd03165
    Location:104 → 195
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:8 → 223
    Tetraspannin; Tetraspanin family
Nucleotide Protein
Heading Accession and Version

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