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Btnl10 butyrophilin-like 10 [ Mus musculus (house mouse) ]

Gene ID: 192194, updated on 2-Nov-2024

Summary

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Official Symbol
Btnl10provided by MGI
Official Full Name
butyrophilin-like 10provided by MGI
Primary source
MGI:MGI:2182073
See related
Ensembl:ENSMUSG00000020490 AllianceGenome:MGI:2182073
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Butr1; BUTR-1
Summary
Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in liver lobe. Orthologous to human BTNL10P (butyrophilin like 10, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in liver E14.5 (RPKM 10.9), liver E14 (RPKM 9.9) and 3 other tissues See more
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Genomic context

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See Btnl10 in Genome Data Viewer
Location:
11 B1.3; 11 36.37 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58808703..58817791)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58917877..58926965)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 39 Neighboring gene STARR-positive B cell enhancer ABC_E2990 Neighboring gene predicted gene 12257 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58741489-58741672 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58741803-58741956 Neighboring gene STARR-positive B cell enhancer ABC_E8409 Neighboring gene ring finger protein 187 Neighboring gene predicted gene, 51864 Neighboring gene STARR-positive B cell enhancer ABC_E3954 Neighboring gene H2B clustered histone 27

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
butyrophilin-like protein 10
Names
butyrophilin related 1
butyrophilin-like protein BUTR-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363414.1 → NP_001350343.1  butyrophilin-like protein 10 variant 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AK143638, AL662809
    Consensus CDS
    CCDS88163.1
    Related
    ENSMUSP00000063279.7, ENSMUST00000069941.13
    Conserved Domains (3) summary
    cd05713
    Location:47 → 146
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    cl02614
    Location:301 → 471
    SPRY; SPRY domain
    cl11960
    Location:151 → 229
    Ig; Immunoglobulin domain

  2. NM_138678.2 → NP_619619.2  butyrophilin-like protein 10 variant 2 precursor

    See identical proteins and their annotated locations for NP_619619.2

    Status: VALIDATED

    Source sequence(s)
    AL662809
    Consensus CDS
    CCDS24753.1
    UniProtKB/Swiss-Prot
    A2AB75, Q8C0U8, Q9JK39
    Related
    ENSMUSP00000020792.6, ENSMUST00000020792.12
    Conserved Domains (3) summary
    cd05713
    Location:47 → 146
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:39 → 145
    IG_like; Immunoglobulin like
    cl11960
    Location:152 → 231
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    58808703..58817791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532533.3 → XP_006532596.1  butyrophilin-like protein 10 isoform X1

    See identical proteins and their annotated locations for XP_006532596.1

    UniProtKB/Swiss-Prot
    Q9JK39
    Conserved Domains (3) summary
    cd05713
    Location:47 → 146
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    cl02614
    Location:301 → 471
    SPRY; SPRY domain
    cl11960
    Location:151 → 229
    Ig; Immunoglobulin domain

  2. XM_006532534.3 → XP_006532597.1  butyrophilin-like protein 10 isoform X2

    Conserved Domains (3) summary
    cd05713
    Location:47 → 146
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    pfam13765
    Location:303 → 351
    PRY; SPRY-associated domain
    cl11960
    Location:151 → 229
    Ig; Immunoglobulin domain

  3. XM_011248809.2 → XP_011247111.1  butyrophilin-like protein 10 isoform X3

    Conserved Domains (2) summary
    cd05713
    Location:47 → 146
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    cl11960
    Location:151 → 229
    Ig; Immunoglobulin domain

  4. XM_006532535.5 → XP_006532598.1  butyrophilin-like protein 10 isoform X4

    Conserved Domains (2) summary
    cd05713
    Location:47 → 146
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    cl11960
    Location:151 → 229
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9JK39.2 GenPept UniProtKB/Swiss-Prot:Q9JK39

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