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Crygn crystallin, gamma N [ Mus musculus (house mouse) ]

Gene ID: 214301, updated on 28-Oct-2024

Summary

Official Symbol
Crygnprovided by MGI
Official Full Name
crystallin, gamma Nprovided by MGI
Primary source
MGI:MGI:2449167
See related
Ensembl:ENSMUSG00000038135 AllianceGenome:MGI:2449167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in eyelid epithelium and lens. Orthologous to human CRYGN (crystallin gamma N). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Crygn in Genome Data Viewer
Location:
5 A3; 5 11.93 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24956000..24962846, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24751002..24757848, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm394 Neighboring gene negative regulator of ubiquitin-like proteins 1 Neighboring gene WD repeat domain 86 Neighboring gene STARR-seq mESC enhancer starr_12647 Neighboring gene STARR-seq mESC enhancer starr_12648 Neighboring gene predicted gene, 42231 Neighboring gene STARR-seq mESC enhancer starr_12649 Neighboring gene predicted gene, 33591 Neighboring gene STARR-positive B cell enhancer ABC_E666 Neighboring gene STARR-seq mESC enhancer starr_12651 Neighboring gene Ras homolog enriched in brain Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit, opposite strand 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of eye lens IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in eye development IEA
Inferred from Electronic Annotation
more info
 
involved_in lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in visual perception IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
gamma-crystallin N
Names
gamma-N-crystallin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153076.3NP_694716.2  gamma-crystallin N

    See identical proteins and their annotated locations for NP_694716.2

    Status: VALIDATED

    Source sequence(s)
    AC137938, AF445456, CF738166
    Consensus CDS
    CCDS19129.1
    UniProtKB/Swiss-Prot
    Q0IJ73, Q0VAU5, Q8VHL5
    Related
    ENSMUSP00000035860.5, ENSMUST00000047119.5
    Conserved Domains (1) summary
    pfam00030
    Location:788
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    24956000..24962846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)