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Edrf1 erythroid differentiation regulatory factor 1 [ Mus musculus (house mouse) ]

Gene ID: 214764, updated on 28-Oct-2024

Summary

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Official Symbol
Edrf1provided by MGI
Official Full Name
erythroid differentiation regulatory factor 1provided by MGI
Primary source
MGI:MGI:1919831
See related
Ensembl:ENSMUSG00000039990 AllianceGenome:MGI:1919831
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2700050L05Rik
Summary
Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human EDRF1 (erythroid differentiation regulatory factor 1). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 5.7), CNS E14 (RPKM 5.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Edrf1 in Genome Data Viewer
Location:
7 F3; 7 77.18 cM
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (133239422..133274710)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (133637544..133673017)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene testis expressed 36 Neighboring gene predicted gene, 35625 Neighboring gene STARR-positive B cell enhancer ABC_E2851 Neighboring gene matrix metallopeptidase 21 Neighboring gene uroporphyrinogen III synthase Neighboring gene STARR-positive B cell enhancer ABC_E4982 Neighboring gene STARR-positive B cell enhancer ABC_E10481 Neighboring gene BRCA2 and CDKN1A interacting protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC27934, MGC58090

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
erythroid differentiation-related factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001408042.1 → NP_001394971.1  erythroid differentiation-related factor 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC127348

  2. NM_001408043.1 → NP_001394972.1  erythroid differentiation-related factor 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC127348
    UniProtKB/TrEMBL
    D3YZE7
    Related
    ENSMUSP00000115641.3, ENSMUST00000128901.9

  3. NM_001408044.1 → NP_001394973.1  erythroid differentiation-related factor 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC127348

  4. NM_178115.5 → NP_835216.3  erythroid differentiation-related factor 1 isoform 1

    See identical proteins and their annotated locations for NP_835216.3

    Status: VALIDATED

    Source sequence(s)
    AC127348
    Consensus CDS
    CCDS21932.2
    UniProtKB/Swiss-Prot
    Q6GQV7, Q80ZY3, Q8R3P5
    UniProtKB/TrEMBL
    E9Q9F9
    Related
    ENSMUSP00000059166.7, ENSMUST00000051169.13

RNA

  1. NR_176447.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC127348

  2. NR_176448.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC127348

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    133239422..133274710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_145995.1: Suppressed sequence

    Description
    NM_145995.1: This RefSeq was temporarily suppressed because the CDS was partial.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GQV7.1 GenPept UniProtKB/Swiss-Prot:Q6GQV7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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