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Lrrc20 leucine rich repeat containing 20 [ Mus musculus (house mouse) ]

Gene ID: 216011, updated on 2-Nov-2024

Summary

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Official Symbol
Lrrc20provided by MGI
Official Full Name
leucine rich repeat containing 20provided by MGI
Primary source
MGI:MGI:2387182
See related
Ensembl:ENSMUSG00000037151 AllianceGenome:MGI:2387182
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Is expressed in embryo and forelimb bud. Orthologous to human LRRC20 (leucine rich repeat containing 20). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in heart adult (RPKM 15.7), mammary gland adult (RPKM 10.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Lrrc20 in Genome Data Viewer
Location:
10 B4; 10 32.22 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (61311579..61418570)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (61475769..61582791)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene nodal growth differentiation factor Neighboring gene eukaryotic translation initiation factor 4E binding protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E3888 Neighboring gene STARR-seq mESC enhancer starr_26847 Neighboring gene RIKEN cDNA D830039M14 gene Neighboring gene STARR-positive B cell enhancer ABC_E6860 Neighboring gene predicted gene, 47593 Neighboring gene oligosaccharyltransferase complex subunit pseudogene Neighboring gene STARR-seq mESC enhancer starr_26850 Neighboring gene predicted gene 28447 Neighboring gene neuropeptide FF receptor 1 Neighboring gene STARR-positive B cell enhancer ABC_E10613 Neighboring gene STARR-positive B cell enhancer ABC_E6861 Neighboring gene pyrophosphatase (inorganic) 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome. Unda BK, et al. Mol Psychiatry, 2023 Apr. PMID 36604605, Free PMC Article
  2. Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Lewandowski JP, et al. Dev Biol, 2015 Oct 1. PMID 26238476, Free PMC Article
  3. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC25719

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153542.1 → NP_705770.1  leucine-rich repeat-containing protein 20

    See identical proteins and their annotated locations for NP_705770.1

    Status: PROVISIONAL

    Source sequence(s)
    BC036304
    Consensus CDS
    CCDS23881.1
    UniProtKB/Swiss-Prot
    Q8CI70
    Related
    ENSMUSP00000048042.8, ENSMUST00000049242.9
    Conserved Domains (4) summary
    cd00116
    Location:22 → 158
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:76 → 98
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:26 → 51
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:98 → 156
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    61311579..61418570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017313885.1 → XP_017169374.1  leucine-rich repeat-containing protein 20 isoform X2

  2. XM_017313884.1 → XP_017169373.1  leucine-rich repeat-containing protein 20 isoform X1

    Conserved Domains (2) summary
    PLN03150
    Location:39 → 110
    PLN03150; hypothetical protein; Provisional
    sd00031
    Location:28 → 48
    LRR_1; leucine-rich repeat [structural motif]

  3. XM_006513472.5 → XP_006513535.1  leucine-rich repeat-containing protein 20 isoform X3

    Conserved Domains (2) summary
    PLN03150
    Location:20 → 91
    PLN03150; hypothetical protein; Provisional
    sd00031
    Location:7 → 29
    LRR_1; leucine-rich repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CI70.1 GenPept UniProtKB/Swiss-Prot:Q8CI70

Gene LinkOut

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