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AU041133 expressed sequence AU041133 [ Mus musculus (house mouse) ]

Gene ID: 216177, updated on 17-Aug-2024

Summary

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Official Symbol
AU041133provided by MGI
Official Full Name
expressed sequence AU041133provided by MGI
Primary source
MGI:MGI:2143755
See related
Ensembl:ENSMUSG00000078435 AllianceGenome:MGI:2143755
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Orthologous to human ZNF101 (zinc finger protein 101) and ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 1.4), bladder adult (RPKM 1.3) and 22 other tissues See more
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Genomic context

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Location:
10 C1; 10 39.72 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (81963843..81989415)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (82128013..82153065)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 873 Neighboring gene sorting nexin family member 27 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2330 Neighboring gene cDNA sequence BC024063 Neighboring gene STARR-seq mESC enhancer starr_27356 Neighboring gene STARR-positive B cell enhancer ABC_E8351 Neighboring gene STARR-positive B cell enhancer ABC_E10631 Neighboring gene predicted gene, 40720 Neighboring gene mitochondrial pyruvate carrier 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC216177

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163064.2 → NP_001156536.1  uncharacterized protein LOC216177

    Status: VALIDATED

    Source sequence(s)
    AC158605
    Consensus CDS
    CCDS78873.1
    UniProtKB/TrEMBL
    A0A0J9YVH3
    Related
    ENSMUSP00000144661.2, ENSMUST00000201286.4
    Conserved Domains (5) summary
    smart00349
    Location:4 → 47
    KRAB; krueppel associated box
    COG5048
    Location:104 → 489
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:332 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 43
    KRAB; KRAB box
    pfam13465
    Location:428 → 453
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    81963843..81989415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245024.2 → XP_030100884.1  uncharacterized protein LOC216177 isoform X2

  2. XM_036155742.1 → XP_036011635.1  uncharacterized protein LOC216177 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:140 → 477
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:312 → 332
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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