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Ccdc85a coiled-coil domain containing 85A [ Mus musculus (house mouse) ]

Gene ID: 216613, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc85aprovided by MGI
Official Full Name
coiled-coil domain containing 85Aprovided by MGI
Primary source
MGI:MGI:2445069
See related
Ensembl:ENSMUSG00000032878 AllianceGenome:MGI:2445069
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in adherens junction. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human CCDC85A (coiled-coil domain containing 85A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in CNS E18 (RPKM 3.5), frontal lobe adult (RPKM 3.1) and 13 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc85a in Genome Data Viewer
Location:
11 A3.3; 11 16.22 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (28335688..28537234, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (28385684..28587234, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_28995 Neighboring gene STARR-seq mESC enhancer starr_28996 Neighboring gene STARR-seq mESC enhancer starr_28997 Neighboring gene predicted gene 12080 Neighboring gene STARR-seq mESC enhancer starr_28998 Neighboring gene STARR-seq mESC enhancer starr_28999 Neighboring gene STARR-seq mESC enhancer starr_29000 Neighboring gene STARR-seq mESC enhancer starr_29001 Neighboring gene STARR-seq mESC enhancer starr_29003 Neighboring gene STARR-seq mESC enhancer starr_29004 Neighboring gene STARR-seq mESC enhancer starr_29005 Neighboring gene STARR-seq mESC enhancer starr_29006 Neighboring gene cytochrome b5 domain containing 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_29007 Neighboring gene STARR-seq mESC enhancer starr_29008 Neighboring gene STARR-seq mESC enhancer starr_29009 Neighboring gene STARR-seq mESC enhancer starr_29010 Neighboring gene STARR-seq mESC enhancer starr_29011 Neighboring gene RIKEN cDNA 2810471M01 gene Neighboring gene predicted gene, 34075 Neighboring gene microRNA 217 host gene Neighboring gene microRNA 216b Neighboring gene microRNA 216c

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • E030025D05Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
  
located_in adherens junction ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 85A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166661.3 → NP_001160133.1  coiled-coil domain-containing protein 85A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910
    Consensus CDS
    CCDS48760.1
    UniProtKB/Swiss-Prot
    Q5SP85
    Related
    ENSMUSP00000044649.9, ENSMUST00000042534.15
    Conserved Domains (1) summary
    pfam10226
    Location:29 → 202
    DUF2216; Uncharacterized conserved proteins (DUF2216)

  2. NM_001346759.2 → NP_001333688.1  coiled-coil domain-containing protein 85A isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910
    Consensus CDS
    CCDS83786.1
    UniProtKB/TrEMBL
    E0CX32
    Related
    ENSMUSP00000124972.2, ENSMUST00000146385.9

  3. NM_001404024.1 → NP_001390953.1  coiled-coil domain-containing protein 85A isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910

  4. NM_001404025.1 → NP_001390954.1  coiled-coil domain-containing protein 85A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910

  5. NM_001404026.1 → NP_001390955.1  coiled-coil domain-containing protein 85A isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910

  6. NM_001404027.1 → NP_001390956.1  coiled-coil domain-containing protein 85A isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910

  7. NM_181577.6 → NP_853555.2  coiled-coil domain-containing protein 85A isoform 1

    See identical proteins and their annotated locations for NP_853555.2

    Status: VALIDATED

    Source sequence(s)
    AL929280, BX255910
    Consensus CDS
    CCDS24489.1
    UniProtKB/Swiss-Prot
    Q5SP85, Q69Z68, Q6NZL9, Q8BGZ5, Q8BLC5, Q8VCC5
    Related
    ENSMUSP00000090941.4, ENSMUST00000093253.10
    Conserved Domains (1) summary
    pfam10226
    Location:29 → 202
    DUF2216; Uncharacterized conserved proteins (DUF2216)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    28335688..28537234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514657.5 → XP_006514720.1  coiled-coil domain-containing protein 85A isoform X3

    Conserved Domains (3) summary
    PHA03269
    Location:137 → 255
    PHA03269; envelope glycoprotein C; Provisional
    pfam10226
    Location:6 → 122
    CCDC85; CCDC85 family
    pfam15449
    Location:137 → 430
    Retinal; Retinal protein

  2. XM_011243694.3 → XP_011241996.1  coiled-coil domain-containing protein 85A isoform X7

    Conserved Domains (2) summary
    PHA03269
    Location:217 → 335
    PHA03269; envelope glycoprotein C; Provisional
    pfam10226
    Location:29 → 202
    CCDC85; CCDC85 family

  3. XM_036156536.1 → XP_036012429.1  coiled-coil domain-containing protein 85A isoform X4

    Conserved Domains (2) summary
    PHA03269
    Location:217 → 335
    PHA03269; envelope glycoprotein C; Provisional
    pfam10226
    Location:29 → 202
    CCDC85; CCDC85 family

  4. XM_036156537.1 → XP_036012430.1  coiled-coil domain-containing protein 85A isoform X5

    Conserved Domains (2) summary
    PHA03269
    Location:217 → 335
    PHA03269; envelope glycoprotein C; Provisional
    pfam10226
    Location:29 → 202
    CCDC85; CCDC85 family

RNA

  1. XR_004936912.1 RNA Sequence

  2. XR_004936910.1 RNA Sequence

  3. XR_004936911.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001166662.1: Suppressed sequence

    Description
    NM_001166662.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SP85.1 GenPept UniProtKB/Swiss-Prot:Q5SP85

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