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FDFT1 - farnesyl-diphosphate farnesyltransferase 1

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]

Genes similar to FDFT1

NCBI Orthologs

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Species Gene Architecture aa