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Ccdc166 coiled-coil domain containing 166 [ Mus musculus (house mouse) ]

Gene ID: 223648, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc166provided by MGI
Official Full Name
coiled-coil domain containing 166provided by MGI
Primary source
MGI:MGI:1925902
See related
Ensembl:ENSMUSG00000098176 AllianceGenome:MGI:1925902
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410075B13Rik
Summary
Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human CCDC166 (coiled-coil domain containing 166). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in colon adult (RPKM 5.3), whole brain E14.5 (RPKM 4.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc166 in Genome Data Viewer
Location:
15 D3; 15 35.18 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75851721..75854134, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75979872..75982285, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2, subunit 3, pseudogene 1 Neighboring gene zinc finger protein 707 Neighboring gene mitogen-activated protein kinase 15 Neighboring gene family with sequence similarity 83, member H Neighboring gene IQ motif and ankyrin repeat containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC37569

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 166

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163518.1 → NP_001156990.1  coiled-coil domain-containing protein 166 isoform 2

    See identical proteins and their annotated locations for NP_001156990.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) retains an intron resulting in a frameshift, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC116487
    Consensus CDS
    CCDS59620.1
    UniProtKB/TrEMBL
    Q0P5Z5
    Related
    ENSMUSP00000138510.2, ENSMUST00000182172.2
    Conserved Domains (1) summary
    pfam13863
    Location:30 → 143
    DUF4200; Domain of unknown function (DUF4200)

  2. NM_146059.2 → NP_666171.2  coiled-coil domain-containing protein 166 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
    Source sequence(s)
    AC116487
    Consensus CDS
    CCDS59621.1
    UniProtKB/TrEMBL
    S4R181
    Related
    ENSMUSP00000138115.2, ENSMUST00000183130.3
    Conserved Domains (1) summary
    pfam14988
    Location:67 → 260
    DUF4515; Domain of unknown function (DUF4515)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    75851721..75854134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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