U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mroh1 maestro heat-like repeat family member 1 [ Mus musculus (house mouse) ]

Gene ID: 223658, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Mroh1provided by MGI
Official Full Name
maestro heat-like repeat family member 1provided by MGI
Primary source
MGI:MGI:2442558
See related
Ensembl:ENSMUSG00000022558 AllianceGenome:MGI:2442558
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Heatr7a; D330001F17Rik
Summary
Predicted to be active in cytoplasm. Orthologous to human MROH1 (maestro heat like repeat family member 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 16.4), kidney adult (RPKM 15.1) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Mroh1 in Genome Data Viewer
Location:
15 D3; 15 35.8 cM
Exon count:
49
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (76264638..76337239)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (76380438..76453039)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11592 Neighboring gene STARR-positive B cell enhancer ABC_E1912 Neighboring gene HGH1 homolog Neighboring gene testis-specific serine kinase 5 Neighboring gene microRNA 6954 Neighboring gene block of proliferation 1 Neighboring gene scleraxis scleraxis bHLH transcription factor Neighboring gene STARR-positive B cell enhancer ABC_E5490 Neighboring gene heat shock factor 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. WDFY4 is required for cross-presentation in response to viral and tumor antigens. Theisen DJ, et al. Science, 2018 Nov 9. PMID 30409884, Free PMC Article
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
  3. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, et al. Cell, 2011 May 13. PMID 21565611, Free PMC Article
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
maestro heat-like repeat-containing protein family member 1
Names
HEAT repeat containing 7A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162489.1 → NP_001155961.1  maestro heat-like repeat-containing protein family member 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon and differs in the 3' CDS and UTR compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC155074
    Consensus CDS
    CCDS49652.1
    UniProtKB/TrEMBL
    D3Z624, Q80T84
    Related
    ENSMUSP00000090256.5, ENSMUST00000092595.11

  2. NM_175457.4 → NP_780666.3  maestro heat-like repeat-containing protein family member 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC155074, AC157566, AK052153, AK147897
    Consensus CDS
    CCDS49651.1
    UniProtKB/TrEMBL
    E0CZ22
    Related
    ENSMUSP00000094115.5, ENSMUST00000096385.11

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    76264638..76337239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159337.1 → XP_036015230.1  maestro heat-like repeat-containing protein family member 1 isoform X7

  2. XM_036159338.1 → XP_036015231.1  maestro heat-like repeat-containing protein family member 1 isoform X10

  3. XM_036159339.1 → XP_036015232.1  maestro heat-like repeat-containing protein family member 1 isoform X11

  4. XM_030248484.1 → XP_030104344.1  maestro heat-like repeat-containing protein family member 1 isoform X12

  5. XM_036159343.1 → XP_036015236.1  maestro heat-like repeat-containing protein family member 1 isoform X16

    UniProtKB/TrEMBL
    Q80T84

  6. XM_036159332.1 → XP_036015225.1  maestro heat-like repeat-containing protein family member 1 isoform X1

  7. XM_036159334.1 → XP_036015227.1  maestro heat-like repeat-containing protein family member 1 isoform X3

  8. XM_036159333.1 → XP_036015226.1  maestro heat-like repeat-containing protein family member 1 isoform X2

  9. XM_036159336.1 → XP_036015229.1  maestro heat-like repeat-containing protein family member 1 isoform X4

  10. XM_011245569.1 → XP_011243871.1  maestro heat-like repeat-containing protein family member 1 isoform X5

  11. XM_011245571.1 → XP_011243873.1  maestro heat-like repeat-containing protein family member 1 isoform X8

  12. XM_011245570.1 → XP_011243872.1  maestro heat-like repeat-containing protein family member 1 isoform X6

  13. XM_011245572.1 → XP_011243874.1  maestro heat-like repeat-containing protein family member 1 isoform X9

  14. XM_036159340.1 → XP_036015233.1  maestro heat-like repeat-containing protein family member 1 isoform X13

  15. XM_030248486.2 → XP_030104346.1  maestro heat-like repeat-containing protein family member 1 isoform X14

  16. XM_036159342.1 → XP_036015235.1  maestro heat-like repeat-containing protein family member 1 isoform X15

    Conserved Domains (1) summary
    sd00044
    Location:1211 → 1247
    HEAT; HEAT repeat [structural motif]

RNA

  1. XR_003951365.1 RNA Sequence

  2. XR_004938821.1 RNA Sequence

  3. XR_004938822.1 RNA Sequence

  4. XR_004938819.1 RNA Sequence

  5. XR_004938816.1 RNA Sequence

  6. XR_004938817.1 RNA Sequence

  7. XR_004938818.1 RNA Sequence

  8. XR_004938820.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools