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Dnah7b dynein, axonemal, heavy chain 7B [ Mus musculus (house mouse) ]

Gene ID: 227058, updated on 2-Nov-2024

Summary

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Official Symbol
Dnah7bprovided by MGI
Official Full Name
dynein, axonemal, heavy chain 7Bprovided by MGI
Primary source
MGI:MGI:2684953
See related
Ensembl:ENSMUSG00000041144 AllianceGenome:MGI:2684953
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm107; Dnahc7b
Summary
Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility. Predicted to act upstream of or within cilium movement and inner dynein arm assembly. Predicted to be located in cytosol. Predicted to be part of inner dynein arm. Predicted to be active in 9+2 motile cilium. Is expressed in spermatozoon and testis. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human DNAH7 (dynein axonemal heavy chain 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 4.9), CNS E14 (RPKM 0.9) and 7 other tissues See more
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Genomic context

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See Dnah7b in Genome Data Viewer
Location:
1 C1.1; 1 23.96 cM
Exon count:
76
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (46105232..46412711)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (46066071..46373551)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase 2 Neighboring gene asparagine synthetase domain containing 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_00825 Neighboring gene predicted gene, 31046 Neighboring gene STARR-seq mESC enhancer starr_00826 Neighboring gene STARR-seq mESC enhancer starr_00827 Neighboring gene STARR-seq mESC enhancer starr_00828 Neighboring gene nuclear encoded rRNA 5S 211 Neighboring gene heat shock protein 8 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. Dong F, et al. J Cell Biol, 2014 Jan 20. PMID 24421334, Free PMC Article
  2. Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. Neesen J, et al. Gene, 1997 Oct 24. PMID 9373155
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dynein intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dynein light intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables minus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cilium movement ISO
Inferred from Sequence Orthology
more info
  
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within inner dynein arm assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in 9+2 motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
part_of inner dynein arm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of inner dynein arm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
dynein, axonemal, heavy chain 7B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368717.1 → NP_001355646.1  dynein, axonemal, heavy chain 7B

    Status: VALIDATED

    Source sequence(s)
    AC108850, AC122879, AC125310
    Consensus CDS
    CCDS87825.1
    UniProtKB/TrEMBL
    A0A571BD48, L7N1Y0
    Related
    ENSMUSP00000158612.2, ENSMUST00000238212.2
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3666
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2963 → 3179
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3720 → 4020
    Dynein_C; Dynein heavy chain C-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    46105232..46412711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238490.4 → XP_011236792.1  dynein, axonemal, heavy chain 7B isoform X1

    See identical proteins and their annotated locations for XP_011236792.1

    UniProtKB/TrEMBL
    A0A571BD48, L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3666
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2963 → 3179
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3720 → 4020
    Dynein_C; Dynein heavy chain C-terminal domain

  2. XM_006495931.5 → XP_006495994.1  dynein, axonemal, heavy chain 7B isoform X19

    Conserved Domains (6) summary
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12775
    Location:1938 → 2118
    AAA_7; P-loop containing dynein motor region D3
    pfam17852
    Location:1782 → 1929
    Dynein_AAA_lid; Dynein heavy chain AAA lid domain
    pfam17857
    Location:2152 → 2211
    AAA_lid_1; AAA+ lid domain
    cl38936
    Location:1604 → 1747
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_006495929.5 → XP_006495992.1  dynein, axonemal, heavy chain 7B isoform X17

    Conserved Domains (6) summary
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12775
    Location:1938 → 2118
    AAA_7; P-loop containing dynein motor region D3
    pfam17852
    Location:1782 → 1929
    Dynein_AAA_lid; Dynein heavy chain AAA lid domain
    pfam17857
    Location:2152 → 2211
    AAA_lid_1; AAA+ lid domain
    cl38936
    Location:1604 → 1747
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_006495930.5 → XP_006495993.1  dynein, axonemal, heavy chain 7B isoform X18

    Conserved Domains (6) summary
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12775
    Location:1938 → 2118
    AAA_7; P-loop containing dynein motor region D3
    pfam17852
    Location:1782 → 1929
    Dynein_AAA_lid; Dynein heavy chain AAA lid domain
    pfam17857
    Location:2152 → 2211
    AAA_lid_1; AAA+ lid domain
    cl38936
    Location:1604 → 1747
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  5. XM_011238495.4 → XP_011236797.1  dynein, axonemal, heavy chain 7B isoform X13

    Conserved Domains (8) summary
    pfam12777
    Location:2587 → 2866
    MT; Microtubule-binding stalk of dynein motor
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12775
    Location:1938 → 2118
    AAA_7; P-loop containing dynein motor region D3
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam17852
    Location:1782 → 1929
    Dynein_AAA_lid; Dynein heavy chain AAA lid domain
    pfam17857
    Location:2152 → 2247
    AAA_lid_1; AAA+ lid domain
    cl38936
    Location:1604 → 1747
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  6. XM_006495928.5 → XP_006495991.1  dynein, axonemal, heavy chain 7B isoform X15

    Conserved Domains (8) summary
    pfam12777
    Location:2587 → 2686
    MT; Microtubule-binding stalk of dynein motor
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12775
    Location:1938 → 2118
    AAA_7; P-loop containing dynein motor region D3
    pfam12780
    Location:2311 → 2573
    AAA_8; P-loop containing dynein motor region D4
    pfam17852
    Location:1782 → 1929
    Dynein_AAA_lid; Dynein heavy chain AAA lid domain
    pfam17857
    Location:2152 → 2247
    AAA_lid_1; AAA+ lid domain
    cl38936
    Location:1604 → 1747
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  7. XM_011238494.4 → XP_011236796.1  dynein, axonemal, heavy chain 7B isoform X12

    Conserved Domains (9) summary
    pfam12777
    Location:2587 → 2933
    MT; Microtubule-binding stalk of dynein motor
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12775
    Location:1938 → 2118
    AAA_7; P-loop containing dynein motor region D3
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2963 → 3033
    AAA_9; ATP-binding dynein motor region D5
    pfam17852
    Location:1782 → 1929
    Dynein_AAA_lid; Dynein heavy chain AAA lid domain
    pfam17857
    Location:2152 → 2247
    AAA_lid_1; AAA+ lid domain
    cl38936
    Location:1604 → 1747
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  8. XM_006495925.5 → XP_006495988.1  dynein, axonemal, heavy chain 7B isoform X11

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (5) summary
    COG5245
    Location:797 → 3666
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2963 → 3179
    AAA_9; ATP-binding dynein motor region D5

  9. XM_006495915.5 → XP_006495978.1  dynein, axonemal, heavy chain 7B isoform X4

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3610
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2963 → 3179
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3658 → 3958
    Dynein_C; Dynein heavy chain C-terminal domain

  10. XM_006495916.5 → XP_006495979.1  dynein, axonemal, heavy chain 7B isoform X6

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3591
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2236 → 2496
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2888 → 3104
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3645 → 3945
    Dynein_C; Dynein heavy chain C-terminal domain

  11. XM_006495913.5 → XP_006495976.1  dynein, axonemal, heavy chain 7B isoform X2

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3633
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1583
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2278 → 2538
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2930 → 3146
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3687 → 3987
    Dynein_C; Dynein heavy chain C-terminal domain

  12. XM_036164345.1 → XP_036020238.1  dynein, axonemal, heavy chain 7B isoform X5

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3595
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1219 → 1545
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2240 → 2502
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2892 → 3108
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3649 → 3949
    Dynein_C; Dynein heavy chain C-terminal domain

  13. XM_006495914.5 → XP_006495977.1  dynein, axonemal, heavy chain 7B isoform X3

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3619
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1160
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1243 → 1569
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2264 → 2524
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2916 → 3132
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3673 → 3973
    Dynein_C; Dynein heavy chain C-terminal domain

  14. XM_030253646.2 → XP_030109506.1  dynein, axonemal, heavy chain 7B isoform X8

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:618 → 3487
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:578 → 983
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1111 → 1437
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2132 → 2392
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2784 → 3000
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3541 → 3841
    Dynein_C; Dynein heavy chain C-terminal domain

  15. XM_030253644.2 → XP_030109504.1  dynein, axonemal, heavy chain 7B isoform X7

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:711 → 3580
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:671 → 1076
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1204 → 1530
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2225 → 2485
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2877 → 3093
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3634 → 3934
    Dynein_C; Dynein heavy chain C-terminal domain

  16. XM_030253647.2 → XP_030109507.1  dynein, axonemal, heavy chain 7B isoform X8

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:618 → 3487
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:578 → 983
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1111 → 1437
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2132 → 2392
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2784 → 3000
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3541 → 3841
    Dynein_C; Dynein heavy chain C-terminal domain

  17. XM_011238487.4 → XP_011236789.1  dynein, axonemal, heavy chain 7B isoform X1

    See identical proteins and their annotated locations for XP_011236789.1

    UniProtKB/TrEMBL
    A0A571BD48, L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:797 → 3666
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:757 → 1162
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1290 → 1616
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2311 → 2571
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2963 → 3179
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3720 → 4020
    Dynein_C; Dynein heavy chain C-terminal domain

  18. XM_006495920.2 → XP_006495983.1  dynein, axonemal, heavy chain 7B isoform X8

    See identical proteins and their annotated locations for XP_006495983.1

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:618 → 3487
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:578 → 983
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1111 → 1437
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2132 → 2392
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2784 → 3000
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3541 → 3841
    Dynein_C; Dynein heavy chain C-terminal domain

  19. XM_006495921.2 → XP_006495984.1  dynein, axonemal, heavy chain 7B isoform X8

    See identical proteins and their annotated locations for XP_006495984.1

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:618 → 3487
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:578 → 983
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1111 → 1437
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2132 → 2392
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2784 → 3000
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3541 → 3841
    Dynein_C; Dynein heavy chain C-terminal domain

  20. XM_011238492.4 → XP_011236794.1  dynein, axonemal, heavy chain 7B isoform X9

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:601 → 3470
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:561 → 966
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1094 → 1420
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2115 → 2375
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2767 → 2983
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3524 → 3824
    Dynein_C; Dynein heavy chain C-terminal domain

  21. XM_006495923.1 → XP_006495986.1  dynein, axonemal, heavy chain 7B isoform X10

    UniProtKB/TrEMBL
    L7N1Y0
    Conserved Domains (6) summary
    COG5245
    Location:549 → 3418
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam08393
    Location:509 → 914
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1042 → 1368
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2063 → 2323
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2715 → 2931
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3472 → 3772
    Dynein_C; Dynein heavy chain C-terminal domain

  22. XM_030253671.1 → XP_030109531.1  dynein, axonemal, heavy chain 7B isoform X16

    Conserved Domains (5) summary
    COG5245
    Location:36 → 2339
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam12774
    Location:18 → 289
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:984 → 1246
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:1636 → 1852
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:2393 → 2693
    Dynein_C; Dynein heavy chain C-terminal domain

  23. XM_011238496.2 → XP_011236798.1  dynein, axonemal, heavy chain 7B isoform X14

    See identical proteins and their annotated locations for XP_011236798.1

    Conserved Domains (5) summary
    COG5245
    Location:36 → 2372
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam12774
    Location:18 → 322
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:1017 → 1279
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:1669 → 1885
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:2426 → 2726
    Dynein_C; Dynein heavy chain C-terminal domain

  24. XM_006495927.3 → XP_006495990.1  dynein, axonemal, heavy chain 7B isoform X14

    See identical proteins and their annotated locations for XP_006495990.1

    Conserved Domains (5) summary
    COG5245
    Location:36 → 2372
    DYN1; Dynein, heavy chain [Cytoskeleton]
    pfam12774
    Location:18 → 322
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:1017 → 1279
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:1669 → 1885
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:2426 → 2726
    Dynein_C; Dynein heavy chain C-terminal domain

RNA

  1. XR_003954985.2 RNA Sequence

  2. XR_003954980.2 RNA Sequence

  3. XR_373250.5 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001160386.1: Suppressed sequence

    Description
    NM_001160386.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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