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Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 [ Mus musculus (house mouse) ]

Gene ID: 228858, updated on 2-Nov-2024

Summary

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Official Symbol
Gdap1l1provided by MGI
Official Full Name
ganglioside-induced differentiation-associated protein 1-like 1provided by MGI
Primary source
MGI:MGI:2385163
See related
Ensembl:ENSMUSG00000017943 AllianceGenome:MGI:2385163
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gdap1l
Summary
Is expressed in gut; nervous system; and sensory organ. Orthologous to human GDAP1L1 (ganglioside induced differentiation associated protein 1 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in whole brain E14.5 (RPKM 31.9), CNS E18 (RPKM 31.4) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Gdap1l1 in Genome Data Viewer
Location:
2 H3; 2 84.28 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (163280387..163297264)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (163438420..163455324)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene junctophilin 2 Neighboring gene VISTA enhancer mm1646 Neighboring gene predicted gene, 35750 Neighboring gene STARR-seq mESC enhancer starr_06306 Neighboring gene STARR-seq mESC enhancer starr_06307 Neighboring gene STARR-positive B cell enhancer ABC_E2651 Neighboring gene RIKEN cDNA 2900093K20 gene Neighboring gene STARR-positive B cell enhancer ABC_E1608 Neighboring gene oxidative stress responsive serine rich 1 Neighboring gene STARR-seq mESC enhancer starr_06310 Neighboring gene RIKEN cDNA 2310001K24 gene Neighboring gene STARR-positive B cell enhancer ABC_E4516 Neighboring gene fat storage-inducing transmembrane protein 2 Neighboring gene hepatic nuclear factor 4 alpha, opposite strand Neighboring gene R3H domain containing-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Psoriasiform Inflammation Is Associated with Mitochondrial Fission/GDAP1L1 Signaling in Macrophages. Alalaiwe A, et al. Int J Mol Sci, 2021 Sep 27. PMID 34638757, Free PMC Article
  2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Psoriasiform Inflammation Is Associated with Mitochondrial Fission/GDAP1L1 Signaling in Macrophages.
    Title: Psoriasiform Inflammation Is Associated with Mitochondrial Fission/GDAP1L1 Signaling in Macrophages.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC28116

General protein information

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Preferred Names
ganglioside-induced differentiation-associated protein 1-like 1
Names
GDAP1-L1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001406429.1 → NP_001393358.1  ganglioside-induced differentiation-associated protein 1-like 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL591488

  2. NM_144891.3 → NP_659140.2  ganglioside-induced differentiation-associated protein 1-like 1 isoform 1

    See identical proteins and their annotated locations for NP_659140.2

    Status: VALIDATED

    Source sequence(s)
    AL591488
    Consensus CDS
    CCDS50791.1
    UniProtKB/Swiss-Prot
    A2A5I0, Q8VE33
    UniProtKB/TrEMBL
    Q3USC7
    Related
    ENSMUSP00000018087.7, ENSMUST00000018087.13
    Conserved Domains (3) summary
    COG0625
    Location:47 → 314
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cd03052
    Location:47 → 119
    GST_N_GDAP1; GST_N family, Ganglioside-induced differentiation-associated protein 1 (GDAP1) subfamily; GDAP1 was originally identified as a highly expressed gene at the differentiated stage of GD3 synthase-transfected cells. More recently, mutations in GDAP1 have ...
    cl02776
    Location:201 → 311
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

RNA

  1. NR_153379.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK140488, AK141371

  2. NR_176072.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL591488

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    163280387..163297264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VE33.1 GenPept UniProtKB/Swiss-Prot:Q8VE33

Gene LinkOut

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