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B3gnt4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 [ Mus musculus (house mouse) ]

Gene ID: 231727, updated on 2-Nov-2024

Summary

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Official Symbol
B3gnt4provided by MGI
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4provided by MGI
Primary source
MGI:MGI:2680208
See related
Ensembl:ENSMUSG00000029431 AllianceGenome:MGI:2680208
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BGnT-4; 1010001G17Rik
Summary
Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to be active in Golgi membrane. Is expressed in embryo. Orthologous to human B3GNT4 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in testis adult (RPKM 8.3), lung adult (RPKM 3.2) and 15 other tissues See more
Orthologs
human all
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Genomic context

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See B3gnt4 in Genome Data Viewer
Location:
5 F; 5 63.02 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (123646519..123649945)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (123508461..123511882)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene interleukin 31 Neighboring gene leucine rich repeat containing 43 Neighboring gene diablo, IAP-binding mitochondrial protein Neighboring gene STARR-positive B cell enhancer ABC_E2175 Neighboring gene microRNA 7647 Neighboring gene VPS33A CORVET/HOPS core subunit Neighboring gene STARR-positive B cell enhancer mm9_chr5:123993667-123993967 Neighboring gene STARR-positive B cell enhancer ABC_E2176

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. Jerome-Majewska LA, et al. Dev Biol, 2010 May 1. PMID 20178780, Free PMC Article
  2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851
  5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in poly-N-acetyllactosamine biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in poly-N-acetyllactosamine biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4
Names
beta-1,3-Gn-T4
beta3Gn-T4
NP_001369783.1
NP_941013.2
XP_006530376.1
XP_011246501.1
XP_011246502.1
XP_036020986.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001382854.1 → NP_001369783.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4

    Status: VALIDATED

    Source sequence(s)
    AC157931
    UniProtKB/Swiss-Prot
    E9QPF4, Q1RLK6, Q923H4
    Conserved Domains (1) summary
    cl21608
    Location:106 → 295
    Galactosyl_T; Galactosyltransferase

  2. NM_198611.2 → NP_941013.2  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4

    See identical proteins and their annotated locations for NP_941013.2

    Status: VALIDATED

    Source sequence(s)
    AC157931, BC115755
    Consensus CDS
    CCDS19665.1
    UniProtKB/Swiss-Prot
    E9QPF4, Q1RLK6, Q923H4
    Related
    ENSMUSP00000031384.6, ENSMUST00000031384.6
    Conserved Domains (1) summary
    cl21608
    Location:106 → 295
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    123646519..123649945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530313.5 → XP_006530376.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 isoform X2

    See identical proteins and their annotated locations for XP_006530376.1

    UniProtKB/Swiss-Prot
    E9QPF4, Q1RLK6, Q923H4
    Conserved Domains (1) summary
    cl21608
    Location:106 → 295
    Galactosyl_T; Galactosyltransferase

  2. XM_036165093.1 → XP_036020986.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 isoform X2

    UniProtKB/Swiss-Prot
    E9QPF4, Q1RLK6, Q923H4
    Conserved Domains (1) summary
    cl21608
    Location:106 → 295
    Galactosyl_T; Galactosyltransferase

  3. XM_011248200.3 → XP_011246502.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 isoform X2

    See identical proteins and their annotated locations for XP_011246502.1

    UniProtKB/Swiss-Prot
    E9QPF4, Q1RLK6, Q923H4
    Conserved Domains (1) summary
    cl21608
    Location:106 → 295
    Galactosyl_T; Galactosyltransferase

  4. XM_011248199.3 → XP_011246501.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 isoform X1

    Conserved Domains (1) summary
    cl21608
    Location:166 → 355
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1RLK6.2 GenPept UniProtKB/Swiss-Prot:Q1RLK6

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