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Kctd14 potassium channel tetramerisation domain containing 14 [ Mus musculus (house mouse) ]

Gene ID: 233529, updated on 2-Nov-2024

Summary

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Official Symbol
Kctd14provided by MGI
Official Full Name
potassium channel tetramerisation domain containing 14provided by MGI
Primary source
MGI:MGI:1289222
See related
Ensembl:ENSMUSG00000051727 AllianceGenome:MGI:1289222
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D7Ertd760e
Summary
Is expressed in testis and urogenital ridge. Orthologous to human KCTD14 (potassium channel tetramerization domain containing 14). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in ovary adult (RPKM 44.5), liver E14.5 (RPKM 6.4) and 12 other tissues See more
Orthologs
human all
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Genomic context

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See Kctd14 in Genome Data Viewer
Location:
7 E1; 7 53.51 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (97085587..97108764)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (97436380..97459557)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19594 Neighboring gene thyroid hormone responsive Neighboring gene STARR-seq mESC enhancer starr_19596 Neighboring gene predicted gene, 32945 Neighboring gene STARR-positive B cell enhancer ABC_E4950 Neighboring gene integrator complex subunit 4 Neighboring gene predicted gene, 24412 Neighboring gene adipogenesis associated Mth938 domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. WT1-mediated gene regulation in early urogenital ridge development. Klattig J, et al. Sex Dev, 2007. PMID 18391535
  2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein KCTD14
Names
potassium channel tetramerization domain containing 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010826.3 → NP_001010826.2  BTB/POZ domain-containing protein KCTD14 isoform b

    See identical proteins and their annotated locations for NP_001010826.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, compared to variant 1, resulting in an isoform (b) that has a distinct N-terminus and is shorter than isoform a. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AC172193, AK145279, BY735425, CK791017, EH106497
    Consensus CDS
    CCDS85342.1
    UniProtKB/TrEMBL
    Q5EER8
    Related
    ENSMUSP00000145727.2, ENSMUST00000205577.2
    Conserved Domains (1) summary
    cl38908
    Location:19 → 115
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  2. NM_001012434.3 → NP_001012436.1  BTB/POZ domain-containing protein KCTD14 isoform b

    See identical proteins and their annotated locations for NP_001012436.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1, resulting in an isoform (b) that has a distinct N-terminus and is shorter than isoform a. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AC172193, BY735425, CK791017, EH106497
    Consensus CDS
    CCDS85342.1
    UniProtKB/TrEMBL
    Q5EER8
    Related
    ENSMUSP00000060557.8, ENSMUST00000050732.14
    Conserved Domains (1) summary
    cl38908
    Location:19 → 115
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  3. NM_001136235.1 → NP_001129707.1  BTB/POZ domain-containing protein KCTD14 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AC172193, BG088171, EH106497
    Consensus CDS
    CCDS21459.2
    UniProtKB/TrEMBL
    A0A0U1RNG7
    Related
    ENSMUSP00000145558.2, ENSMUST00000206658.2
    Conserved Domains (2) summary
    smart00225
    Location:73 → 163
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cl02518
    Location:73 → 153
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    97085587..97108764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507607.3 → XP_006507670.2  BTB/POZ domain-containing protein KCTD14 isoform X1

    Conserved Domains (1) summary
    cl38908
    Location:96 → 192
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  2. XM_006507610.3 → XP_006507673.1  BTB/POZ domain-containing protein KCTD14 isoform X3

    UniProtKB/TrEMBL
    A0A0U1RPG8
    Related
    ENSMUSP00000145977.2, ENSMUST00000206279.2
    Conserved Domains (1) summary
    cl38908
    Location:51 → 147
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  3. XM_006507608.3 → XP_006507671.1  BTB/POZ domain-containing protein KCTD14 isoform X2

    See identical proteins and their annotated locations for XP_006507671.1

    UniProtKB/TrEMBL
    Q5EER8
    Conserved Domains (1) summary
    cl38908
    Location:19 → 115
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  4. XM_030242478.2 → XP_030098338.1  BTB/POZ domain-containing protein KCTD14 isoform X2

    UniProtKB/TrEMBL
    Q5EER8
    Conserved Domains (1) summary
    cl38908
    Location:19 → 115
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  5. XM_006507609.3 → XP_006507672.1  BTB/POZ domain-containing protein KCTD14 isoform X2

    See identical proteins and their annotated locations for XP_006507672.1

    UniProtKB/TrEMBL
    Q5EER8
    Conserved Domains (1) summary
    cl38908
    Location:19 → 115
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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