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Pced1b PC-esterase domain containing 1B [ Mus musculus (house mouse) ]

Gene ID: 239647, updated on 2-Nov-2024

Summary

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Official Symbol
Pced1bprovided by MGI
Official Full Name
PC-esterase domain containing 1Bprovided by MGI
Primary source
MGI:MGI:2446270
See related
Ensembl:ENSMUSG00000044250 AllianceGenome:MGI:2446270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam113b
Summary
Orthologous to human PCED1B (PC-esterase domain containing 1B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in spleen adult (RPKM 7.5), ovary adult (RPKM 4.7) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Pced1b in Genome Data Viewer
Location:
15 F1; 15 52.91 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (97143563..97283574)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (97246973..97385693)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39614 Neighboring gene predicted gene, 32885 Neighboring gene predicted gene, 33149 Neighboring gene STARR-seq mESC enhancer starr_39615 Neighboring gene predicted gene, 33253 Neighboring gene predicted gene, 33205 Neighboring gene STARR-positive B cell enhancer mm9_chr15:97089728-97090029 Neighboring gene predicted gene, 57814 Neighboring gene adhesion molecule with Ig like domain 2 Neighboring gene STARR-seq mESC enhancer starr_39616 Neighboring gene high mobility group box 2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8610 Neighboring gene STARR-positive B cell enhancer ABC_E9920 Neighboring gene STARR-positive B cell enhancer ABC_E7414 Neighboring gene predicted gene, 33325 Neighboring gene STARR-positive B cell enhancer ABC_E1484 Neighboring gene STARR-seq mESC enhancer starr_39625 Neighboring gene STARR-seq mESC enhancer starr_39629 Neighboring gene predicted gene, 41393 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:97289192-97289405 Neighboring gene STARR-seq mESC enhancer starr_39631 Neighboring gene STARR-seq mESC enhancer starr_39632 Neighboring gene STARR-seq mESC enhancer starr_39633 Neighboring gene STARR-seq mESC enhancer starr_39634 Neighboring gene predicted gene, 41394

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC47262

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
PC-esterase domain-containing protein 1B
Names
family with sequence similarity 113, member B
protein FAM113B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001416134.1 → NP_001403063.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  2. NM_001416135.1 → NP_001403064.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Related
    ENSMUSP00000154814.2, ENSMUST00000228521.2

  3. NM_001416136.1 → NP_001403065.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  4. NM_001416137.1 → NP_001403066.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  5. NM_001416138.1 → NP_001403067.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  6. NM_001416139.1 → NP_001403068.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  7. NM_001416140.1 → NP_001403069.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  8. NM_001416141.1 → NP_001403070.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  9. NM_001416142.1 → NP_001403071.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  10. NM_001416143.1 → NP_001403072.1  PC-esterase domain-containing protein 1B

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1

  11. NM_172293.5 → NP_758497.1  PC-esterase domain-containing protein 1B

    See identical proteins and their annotated locations for NP_758497.1

    Status: VALIDATED

    Source sequence(s)
    AC102914, AC161194
    Consensus CDS
    CCDS27781.1
    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Related
    ENSMUSP00000055485.7, ENSMUST00000059433.8
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    97143563..97283574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245624.2 → XP_011243926.1  PC-esterase domain-containing protein 1B isoform X1

    See identical proteins and their annotated locations for XP_011243926.1

    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  2. XM_011245626.4 → XP_011243928.1  PC-esterase domain-containing protein 1B isoform X1

    See identical proteins and their annotated locations for XP_011243928.1

    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  3. XM_036159404.1 → XP_036015297.1  PC-esterase domain-containing protein 1B isoform X1

    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  4. XM_011245625.3 → XP_011243927.1  PC-esterase domain-containing protein 1B isoform X1

    See identical proteins and their annotated locations for XP_011243927.1

    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  5. XM_006520967.5 → XP_006521030.1  PC-esterase domain-containing protein 1B isoform X1

    See identical proteins and their annotated locations for XP_006521030.1

    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  6. XM_006520968.5 → XP_006521031.1  PC-esterase domain-containing protein 1B isoform X1

    See identical proteins and their annotated locations for XP_006521031.1

    UniProtKB/Swiss-Prot
    Q5RK34, Q8BGX1
    Conserved Domains (1) summary
    cl01053
    Location:17 → 253
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BGX1.1 GenPept UniProtKB/Swiss-Prot:Q8BGX1

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