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Kcng2 potassium voltage-gated channel, subfamily G, member 2 [ Mus musculus (house mouse) ]

Gene ID: 240444, updated on 28-Oct-2024

Summary

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Official Symbol
Kcng2provided by MGI
Official Full Name
potassium voltage-gated channel, subfamily G, member 2provided by MGI
Primary source
MGI:MGI:3694646
See related
Ensembl:ENSMUSG00000059852 AllianceGenome:MGI:3694646
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable potassium channel regulator activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Orthologous to human KCNG2 (potassium voltage-gated channel modifier subfamily G member 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in heart adult (RPKM 41.8) and thymus adult (RPKM 2.3) See more
Orthologs
human all
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Genomic context

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See Kcng2 in Genome Data Viewer
Location:
18 E3; 18 53.4 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (80337731..80407469, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (80294544..80364254, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene heat shock factor binding protein 1-like 1 Neighboring gene STARR-seq mESC enhancer starr_45175 Neighboring gene solute carrier family 66 member 2 Neighboring gene VISTA enhancer mm152 Neighboring gene predicted gene, 26676 Neighboring gene RIKEN cDNA D330025C20 gene Neighboring gene predicted gene, 29967 Neighboring gene STARR-seq mESC enhancer starr_45177 Neighboring gene CTD phosphatase subunit 1 Neighboring gene predicted gene 9456

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables potassium channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in action potential IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of voltage-gated potassium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
potassium voltage-gated channel subfamily G member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190373.1 → NP_001177302.1  potassium voltage-gated channel subfamily G member 2

    See identical proteins and their annotated locations for NP_001177302.1

    Status: VALIDATED

    Source sequence(s)
    AC145610
    Consensus CDS
    CCDS57127.1
    UniProtKB/TrEMBL
    F7A6P6
    Related
    ENSMUSP00000077112.7, ENSMUST00000077962.8
    Conserved Domains (2) summary
    cl38908
    Location:33 → 127
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    pfam00520
    Location:190 → 429
    Ion_trans; Ion transport protein

  2. NM_001404104.1 → NP_001391033.1  potassium voltage-gated channel subfamily G member 2

    Status: VALIDATED

    Source sequence(s)
    AC145610
    UniProtKB/TrEMBL
    F7A6P6

  3. NM_001404105.1 → NP_001391034.1  potassium voltage-gated channel subfamily G member 2

    Status: VALIDATED

    Source sequence(s)
    AC145610
    UniProtKB/TrEMBL
    F7A6P6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    80337731..80407469 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317904.3 → XP_017173393.1  potassium voltage-gated channel subfamily G member 2 isoform X1

    UniProtKB/TrEMBL
    F7A6P6
    Conserved Domains (2) summary
    cl38908
    Location:33 → 127
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    pfam00520
    Location:190 → 429
    Ion_trans; Ion transport protein
Nucleotide Protein Strain
Heading Accession and Version

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