U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam110b family with sequence similarity 110, member B [ Mus musculus (house mouse) ]

Gene ID: 242297, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Fam110bprovided by MGI
Official Full Name
family with sequence similarity 110, member Bprovided by MGI
Primary source
MGI:MGI:1916593
See related
Ensembl:ENSMUSG00000049119 AllianceGenome:MGI:1916593
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5031405P22; 1700012H17Rik
Summary
Predicted to be located in cytosol and mitochondrion. Is expressed in cortical plate. Orthologous to human FAM110B (family with sequence similarity 110 member B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 18.0), whole brain E14.5 (RPKM 14.4) and 21 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Fam110b in Genome Data Viewer
Location:
4 A1; 4 2.62 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (5644009..5801101)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (5644009..5801101)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09455 Neighboring gene family with sequence similarity 20, member B pseudogene Neighboring gene STARR-seq mESC enhancer starr_09456 Neighboring gene STARR-seq mESC enhancer starr_09457 Neighboring gene STARR-seq mESC enhancer starr_09458 Neighboring gene STARR-seq mESC enhancer starr_09459 Neighboring gene STARR-seq mESC enhancer starr_09460 Neighboring gene STARR-seq mESC enhancer starr_09461 Neighboring gene STARR-seq mESC enhancer starr_09463 Neighboring gene RIKEN cDNA 4930423M02 gene Neighboring gene STARR-seq mESC enhancer starr_09464 Neighboring gene STARR-seq mESC enhancer starr_09467 Neighboring gene STARR-seq mESC enhancer starr_09468 Neighboring gene STARR-seq mESC enhancer starr_09469 Neighboring gene predicted gene, 24337 Neighboring gene VISTA enhancer mm718 Neighboring gene STARR-seq mESC enhancer starr_09473 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene zinc finger protein 46 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein FAM110B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355716.1 → NP_001342645.1  protein FAM110B

    Status: VALIDATED

    Source sequence(s)
    AK049898, AW049855, BC055683, BY292674
    Consensus CDS
    CCDS17948.1
    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Related
    ENSMUSP00000104017.2, ENSMUST00000108380.2
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  2. NM_173426.3 → NP_775602.1  protein FAM110B

    See identical proteins and their annotated locations for NP_775602.1

    Status: VALIDATED

    Source sequence(s)
    AK049898, AK052596, AK080588, AL772304, AW049855, BY269222
    Consensus CDS
    CCDS17948.1
    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Related
    ENSMUSP00000062734.7, ENSMUST00000054857.13
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    5644009..5801101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537896.4 → XP_006537959.1  protein FAM110B isoform X1

    See identical proteins and their annotated locations for XP_006537959.1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  2. XM_030253522.2 → XP_030109382.1  protein FAM110B isoform X1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  3. XM_030253518.2 → XP_030109378.1  protein FAM110B isoform X1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  4. XM_030253519.1 → XP_030109379.1  protein FAM110B isoform X1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  5. XM_030253523.1 → XP_030109383.1  protein FAM110B isoform X1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  6. XM_030253520.1 → XP_030109380.1  protein FAM110B isoform X1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  7. XM_006537897.1 → XP_006537960.1  protein FAM110B isoform X1

    See identical proteins and their annotated locations for XP_006537960.1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Related
    ENSMUSP00000127942.2, ENSMUST00000171403.2
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus

  8. XM_006537898.5 → XP_006537961.1  protein FAM110B isoform X1

    See identical proteins and their annotated locations for XP_006537961.1

    UniProtKB/Swiss-Prot
    Q3UKH0, Q8C739
    Conserved Domains (2) summary
    pfam14160
    Location:249 → 357
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:17 → 118
    FAM110_N; Centrosome-associated N-terminus
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C739.1 GenPept UniProtKB/Swiss-Prot:Q8C739

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools