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Oog4 oogenesin 4 [ Mus musculus (house mouse) ]

Gene ID: 242737, updated on 17-Aug-2024

Summary

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Official Symbol
Oog4provided by MGI
Official Full Name
oogenesin 4provided by MGI
Primary source
MGI:MGI:2684051
See related
Ensembl:ENSMUSG00000047799 AllianceGenome:MGI:2684051
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E330017M15
Summary
Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
4 E1; 4 77.67 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (143163734..143176894, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (143437164..143450324, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene PRAME like 1 Neighboring gene STARR-seq mESC enhancer starr_11972 Neighboring gene PRAME like 12 Neighboring gene KH-type splicing regulatory protein pseudogene Neighboring gene predicted gene 13041

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte. Dadé S, et al. FEBS Lett, 2003 Dec 18. PMID 14675769
  2. Maternal microRNAs are essential for mouse zygotic development. Tang F, et al. Genes Dev, 2007 Mar 15. PMID 17369397, Free PMC Article
  3. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article
  4. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
oogenesin 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347238.2 → NP_001334167.1  oogenesin 4 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK054346, BC098485, DV644638
    Consensus CDS
    CCDS84817.1
    UniProtKB/TrEMBL
    Q4G0C7, Q7TPS8
    Related
    ENSMUSP00000073325.4, ENSMUST00000073641.4

  2. NM_173773.2 → NP_776134.1  oogenesin 4 isoform 2

    See identical proteins and their annotated locations for NP_776134.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon and uses a downstream translation initiation codon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK054346, DV644638
    Consensus CDS
    CCDS18890.1
    UniProtKB/TrEMBL
    Q7TPS8, Q8BHX9
    Related
    ENSMUSP00000052217.5, ENSMUST00000061277.11

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    143163734..143176894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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