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Ganc glucosidase, alpha; neutral C [ Rattus norvegicus (Norway rat) ]

Gene ID: 24382, updated on 2-Nov-2024

Summary

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Official Symbol
Gancprovided by RGD
Official Full Name
glucosidase, alpha; neutral Cprovided by RGD
Primary source
RGD:2660
See related
EnsemblRapid:ENSRNOG00000024563 AllianceGenome:RGD:2660
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable alpha-1,4-glucosidase activity. Predicted to be involved in N-glycan processing. Orthologous to human GANC (glucosidase alpha, neutral C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 134.7), Thymus (RPKM 76.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ganc in Genome Data Viewer
Location:
3q35
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (127807132..127858995)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (107353369..107406104)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (112173907..112226886)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2, group IVF Neighboring gene ribosomal protein S25, pseudogene 11 Neighboring gene VPS39 subunit of HOPS complex Neighboring gene transmembrane protein 87A Neighboring gene uncharacterized LOC108350445 Neighboring gene small nucleolar RNA SNORA15 Neighboring gene calpain 3 Neighboring gene zinc finger protein 106

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids. Yasue M, et al. Cytogenet Cell Genet, 1991. PMID 1914521
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables alpha-1,4-glucosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-1,4-glucosidase activity ISO
Inferred from Sequence Orthology
more info
  
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
neutral alpha-glucosidase C
Names
neutral C
NP_001139312.1
XP_038960171.1
XP_063139146.1
XP_063139147.1
XP_063139148.1
XP_063139149.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145840.1 → NP_001139312.1  neutral alpha-glucosidase C

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    D4A7G5
    Related
    ENSRNOP00000011369.5, ENSRNOT00000011369.7
    Conserved Domains (3) summary
    cd06603
    Location:352 → 819
    GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
    cd14752
    Location:212 → 352
    GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)
    pfam01055
    Location:333 → 778
    Glyco_hydro_31; Glycosyl hydrolases family 31

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    127807132..127858995
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063283077.1 → XP_063139147.1  neutral alpha-glucosidase C isoform X2

  2. XM_063283078.1 → XP_063139148.1  neutral alpha-glucosidase C isoform X3

  3. XM_063283076.1 → XP_063139146.1  neutral alpha-glucosidase C isoform X1

  4. XM_039104243.2 → XP_038960171.1  neutral alpha-glucosidase C isoform X4

    Conserved Domains (2) summary
    cd06603
    Location:352 → 767
    GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
    cd14752
    Location:212 → 352
    GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)

  5. XM_063283079.1 → XP_063139149.1  neutral alpha-glucosidase C isoform X5

RNA

  1. XR_005501772.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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