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Zfp711 zinc finger protein 711 [ Mus musculus (house mouse) ]

Gene ID: 245595, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp711provided by MGI
Official Full Name
zinc finger protein 711provided by MGI
Primary source
MGI:MGI:3045342
See related
Ensembl:ENSMUSG00000025529 AllianceGenome:MGI:3045342
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf711; 2810409C01Rik; A230078I01Rik
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 97. Orthologous to human ZNF711 (zinc finger protein 711). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in CNS E18 (RPKM 8.3), CNS E14 (RPKM 7.5) and 9 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp711 in Genome Data Viewer
Location:
X E1; X 48.76 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (111510259..111544767)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (112600526..112635070)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47778 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene RIKEN cDNA 2010106E10 gene Neighboring gene premature ovarian failure 1B Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_47779 Neighboring gene replication factor C (activator 1) 4 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. Kasowitz SD, et al. PLoS Genet, 2018 May. PMID 29799838, Free PMC Article
  2. A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum. Farini D, et al. Cell Rep, 2020 Jun 2. PMID 32492419
  3. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
  4. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
zinc finger protein 711

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001381898.1 → NP_001368827.1  zinc finger protein 711 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL831771
    UniProtKB/Swiss-Prot
    A2ANX9
    UniProtKB/TrEMBL
    E9PUP8
    Conserved Domains (3) summary
    COG5048
    Location:425 → 805
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:551 → 571
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:65 → 412
    Zfx_Zfy_act; Zfx / Zfy transcription activation region

  2. NM_001381899.1 → NP_001368828.1  zinc finger protein 711 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL831771
    UniProtKB/Swiss-Prot
    A2ANX9
    UniProtKB/TrEMBL
    F8WGY3
    Conserved Domains (3) summary
    COG5048
    Location:380 → 760
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:506 → 526
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:65 → 367
    Zfx_Zfy_act; Zfx / Zfy transcription activation region

  3. NM_001381900.1 → NP_001368829.1  zinc finger protein 711 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL831771
    UniProtKB/Swiss-Prot
    A2ANX9
    UniProtKB/TrEMBL
    F8WGY3
    Related
    ENSMUSP00000071717.7, ENSMUST00000071814.13
    Conserved Domains (3) summary
    COG5048
    Location:380 → 760
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:506 → 526
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:65 → 367
    Zfx_Zfy_act; Zfx / Zfy transcription activation region

  4. NM_001405551.1 → NP_001392480.1  zinc finger protein 711 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL831771

  5. NM_177747.4 → NP_808415.2  zinc finger protein 711 isoform 1

    See identical proteins and their annotated locations for NP_808415.2

    Status: VALIDATED

    Source sequence(s)
    AL831771
    Consensus CDS
    CCDS41106.1
    UniProtKB/Swiss-Prot
    A2ANX9
    UniProtKB/TrEMBL
    E9PUP8
    Related
    ENSMUSP00000109036.2, ENSMUST00000113409.8
    Conserved Domains (3) summary
    COG5048
    Location:425 → 805
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:551 → 571
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:65 → 412
    Zfx_Zfy_act; Zfx / Zfy transcription activation region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    111510259..111544767
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161957.1 → XP_036017850.1  zinc finger protein 711 isoform X1

    UniProtKB/Swiss-Prot
    A2ANX9
    UniProtKB/TrEMBL
    E9PUP8
    Conserved Domains (3) summary
    COG5048
    Location:425 → 805
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:551 → 571
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:65 → 412
    Zfx_Zfy_act; Zfx / Zfy transcription activation region

  2. XM_036161958.1 → XP_036017851.1  zinc finger protein 711 isoform X2

    UniProtKB/Swiss-Prot
    A2ANX9
    UniProtKB/TrEMBL
    F8WGY3
    Conserved Domains (3) summary
    COG5048
    Location:380 → 760
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:506 → 526
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:65 → 367
    Zfx_Zfy_act; Zfx / Zfy transcription activation region

  3. XM_036161959.1 → XP_036017852.1  zinc finger protein 711 isoform X4

    Conserved Domains (2) summary
    sd00017
    Location:162 → 182
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04704
    Location:2 → 23
    Zfx_Zfy_act; Zfx / Zfy transcription activation region
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2ANX9.1 GenPept UniProtKB/Swiss-Prot:A2ANX9

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