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spe-48 UBA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 245997, updated on 18-Sep-2024

Summary

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Official Symbol
spe-48
Official Full Name
UBA domain-containing protein
Primary source
WormBase:WBGene00021771
Locus tag
CELE_Y51F10.10
See related
AllianceGenome:WB:WBGene00021771
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT I complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See spe-48 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (1950594..1958527, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Aa_trans domain-containing protein;Amino acid transporter transmembrane domain-containing protein Neighboring gene EGF-like domain-containing protein Neighboring gene Defect at low temperature protein 1 Neighboring gene EGF-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. L'Hernault SW, et al. Genetics, 1988 Oct. PMID 3197956, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ESCRT I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ESCRT I complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UBA domain-containing protein
NP_001293398.1
  • Confirmed by transcript evidence
NP_001293399.1
  • Confirmed by transcript evidence
NP_001293400.1
  • Confirmed by transcript evidence
NP_001293401.1
  • Confirmed by transcript evidence
NP_740794.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    1950594..1958527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001306469.2 → NP_001293398.1  UBA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293398.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X5MBH3
    Conserved Domains (1) summary
    cl21463
    Location:280 → 309
    UBA_like_SF; UBA domain-like superfamily

  2. NM_170811.6 → NP_740794.1  UBA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740794.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8WTK0
    Conserved Domains (1) summary
    cl21463
    Location:305 → 334
    UBA_like_SF; UBA domain-like superfamily

  3. NM_001306470.3 → NP_001293399.1  UBA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293399.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X5M5Q2
    Conserved Domains (1) summary
    cl21463
    Location:265 → 294
    UBA_like_SF; UBA domain-like superfamily

  4. NM_001306471.3 → NP_001293400.1  UBA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293400.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X5MD76
    Conserved Domains (1) summary
    cl21463
    Location:290 → 319
    UBA_like_SF; UBA domain-like superfamily

  5. NM_001306472.3 → NP_001293401.1  UBA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293401.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X5MK34
    Conserved Domains (1) summary
    cl21463
    Location:43 → 72
    UBA_like_SF; UBA domain-like superfamily
Nucleotide Protein
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