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Slc7a6os solute carrier family 7, member 6 opposite strand [ Rattus norvegicus (Norway rat) ]

Gene ID: 246187, updated on 2-Nov-2024

Summary

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Official Symbol
Slc7a6osprovided by RGD
Official Full Name
solute carrier family 7, member 6 opposite strandprovided by RGD
Primary source
RGD:708394
See related
EnsemblRapid:ENSRNOG00000020049 AllianceGenome:RGD:708394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in developmental process. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Orthologous to human SLC7A6OS (solute carrier family 7 member 6 opposite strand). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 114.3), Brain (RPKM 97.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc7a6os in Genome Data Viewer
Location:
19q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (51011850..51020514, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (34101978..34110666, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (38180859..38189523, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2, group XV Neighboring gene solute carrier family 7 member 6 Neighboring gene protein arginine methyltransferase 7 Neighboring gene sphingomyelin phosphodiesterase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in developmental process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable RNA polymerase II nuclear localization protein SLC7A6OS

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139328.2 → NP_647544.2  probable RNA polymerase II nuclear localization protein SLC7A6OS

    See identical proteins and their annotated locations for NP_647544.2

    Status: VALIDATED

    Source sequence(s)
    AY098917, BM386170, DY567141
    UniProtKB/TrEMBL
    A6IYW4, G3V8N8
    Related
    ENSRNOP00000027200.5, ENSRNOT00000027200.7
    Conserved Domains (1) summary
    pfam08574
    Location:190 → 254
    DUF1762; Protein of unknown function (DUF1762)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    51011850..51020514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039097474.2 → XP_038953402.1  probable RNA polymerase II nuclear localization protein SLC7A6OS isoform X1

  2. XM_039097475.2 → XP_038953403.1  probable RNA polymerase II nuclear localization protein SLC7A6OS isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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