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prp28 U5 snRNP-associated protein Prp28 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538728, updated on 18-Sep-2024

Summary

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Official Symbol
prp28
Official Full Name
U5 snRNP-associated protein Prp28
Primary source
PomBase:SPCC63.11
Locus tag
SPOM_SPCC63.11
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See prp28 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (857017..859292)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene dolichol kinase Sec59 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene proteasome core particle subunit beta 3 Pup3 Neighboring gene ncRNA Neighboring gene DNAJ (Hsp40) chaperone family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutant allele of rna14 in fission yeast affects pre-mRNA splicing. Yadav S, et al. J Genet, 2016 Jun. PMID 27350684
  2. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
  3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cis assembly of pre-catalytic spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of U5 snRNP ISO
Inferred from Sequence Orthology
more info
  
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
U5 snRNP-associated protein Prp28

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    857017..859292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022975.3 → NP_587984.1  U5 snRNP-associated protein Prp28 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587984.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9Y7T7
    Conserved Domains (4) summary
    smart00487
    Location:264 → 492
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:489 → 619
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:251 → 475
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    TIGR02794
    Location:15 → 56
    tolA_full; TolA protein
Nucleotide Protein
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