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uro1 uricase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538957, updated on 18-Sep-2024

Summary

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Official Symbol
uro1
Official Full Name
uricase
Primary source
PomBase:SPCC1223.09
Locus tag
SPOM_SPCC1223.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See uro1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1857150..1858233, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dihydrofolate reductase/ lysophospholipase fusion protein Dfr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase II transcription elongation factor Eaf1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic studies of purine breakdown in the fission yeast Schizosaccharomyces pombe. Kinghorn JR, et al. Curr Genet, 1984 Feb. PMID 24177583
  2. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
  3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables urate oxidase activity EXP
Inferred from Experiment
more info
 PubMed 
enables urate oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in purine nucleobase catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in urate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in urea metabolic process IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uricase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1857150..1858233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023345.3 → NP_588354.1  uricase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588354.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74409
    Conserved Domains (2) summary
    COG3648
    Location:1 → 296
    UriC; Uricase (urate oxidase) [Secondary metabolites biosynthesis, transport and catabolism]
    cl00263
    Location:12 → 295
    TFold; Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl ...
Nucleotide Protein
Heading Accession and Version

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