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ada2 SAGA complex subunit Ada2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539174, updated on 18-Sep-2024

Summary

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Official Symbol
ada2
Official Full Name
SAGA complex subunit Ada2
Primary source
PomBase:SPCC24B10.08c
Locus tag
SPOM_SPCC24B10.08C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ada2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (915040..916698, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase (AGC family) Gad8 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS17

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The SAGA histone acetyltransferase module targets SMC5/6 to specific genes. Mahrik L, et al. Epigenetics Chromatin, 2023 Feb 16. PMID 36793083, Free PMC Article
  2. Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26. Hirota K, et al. Mol Biol Cell, 2008 Mar. PMID 18199689, Free PMC Article
  3. Nucleosome eviction in mitosis assists condensin loading and chromosome condensation. Toselli-Mollereau E, et al. EMBO J, 2016 Jul 15. PMID 27266525, Free PMC Article
  4. The SAGA histone acetyltransferase complex regulates leucine uptake through the Agp3 permease in fission yeast. Takahashi H, et al. J Biol Chem, 2012 Nov 2. PMID 22992726, Free PMC Article
  5. Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin. Bao K, et al. Genes Dev, 2019 Jan 1. PMID 30573453, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chromatin organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of SAGA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SAGA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of SAGA-type complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SAGA complex subunit Ada2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    915040..916698 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023002.3 → NP_588011.1  SAGA complex subunit Ada2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588011.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7J7
    Conserved Domains (4) summary
    COG5114
    Location:1 → 437
    COG5114; Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
    cd02335
    Location:6 → 54
    ZZ_ADA2; Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
    pfam00249
    Location:65 → 108
    Myb_DNA-binding; Myb-like DNA-binding domain
    pfam04433
    Location:357 → 433
    SWIRM; SWIRM domain
Nucleotide Protein
Heading Accession and Version

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