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lsm8 U6 snRNP-associated protein Lsm8 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539322, updated on 18-Sep-2024

Summary

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Official Symbol
lsm8
Official Full Name
U6 snRNP-associated protein Lsm8
Primary source
PomBase:SPCC1840.10
Locus tag
SPOM_SPCC1840.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lsm8 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003421.2 (2277878..2278303)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquinone biosynthesis protein Coq11 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene exosome subunit Csl4 Neighboring gene OPT oligopeptide transporter family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Hu X, et al. Cell Rep, 2020 Dec 29. PMID 33378677
  2. The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme. Porat J, et al. Nat Commun, 2022 Mar 11. PMID 35277511, Free PMC Article
  3. Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Montemayor EJ, et al. RNA, 2020 Oct. PMID 32518066, Free PMC Article
  4. LARP7 family proteins have conserved function in telomerase assembly. Collopy LC, et al. Nat Commun, 2018 Feb 8. PMID 29422501, Free PMC Article
  5. Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes. Tang W, et al. Nature, 2012 Mar 25. PMID 22446625, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to RNA folding chaperone EXP
Inferred from Experiment
more info
 PubMed 
enables U2 snRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in telomerase holoenzyme complex assembly TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of Lsm2-8 complex EXP
Inferred from Experiment
more info
 PubMed 
part_of U2 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U5 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U6 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of telomerase holoenzyme complex EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
U6 snRNP-associated protein Lsm8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2277878..2278303
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023499.3 → NP_588509.1  U6 snRNP-associated protein Lsm8 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588509.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74483
    Conserved Domains (1) summary
    cd01727
    Location:2 → 90
    LSm8; Like-Sm protein 8
Nucleotide Protein
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