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pof6 exocyst complex subunit Exo5-like, F-box protein Pof6 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539324, updated on 18-Sep-2024

Summary

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Official Symbol
pof6
Official Full Name
exocyst complex subunit Exo5-like, F-box protein Pof6
Primary source
PomBase:SPCC18.04
Locus tag
SPOM_SPCC18.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
sin4
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Genomic context

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See pof6 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (1960109..1962798)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene transporter Neighboring gene ncRNA Neighboring gene shuttle craft like transcriptional regulator Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Rsa4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast. Hermand D, et al. J Biol Chem, 2003 Mar 14. PMID 12511573
  2. Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast. Jourdain I, et al. Biochem J, 2009 May 13. PMID 19243310, Free PMC Article
  3. Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint. Lehmann A, et al. Genes Cells, 2004 May. PMID 15147268
  4. Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF. Tafforeau L, et al. EMBO J, 2006 Oct 4. PMID 17016471, Free PMC Article
  5. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study identified a novel conserved protein, Sip1, as an interacting partner of an essential F-box protein Pof6.
    Title: Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin-like ligase-substrate adaptor activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in Golgi to plasma membrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytic recycling ISO
Inferred from Sequence Orthology
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in septum digestion after cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in cytosol HDA PubMed 
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
  
NOT is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ubiquitin ligase complex ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
exocyst complex subunit Exo5-like, F-box protein Pof6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1960109..1962798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023374.3 → NP_588383.1  exocyst complex subunit Exo5-like, F-box protein Pof6 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588383.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74854
    Conserved Domains (2) summary
    smart00256
    Location:33 → 73
    FBOX; A Receptor for Ubiquitination Targets
    pfam07393
    Location:179 → 862
    Sec10; Exocyst complex component Sec10
Nucleotide Protein
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Molecular Biology Databases
Research Materials