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ppc1 phosphopantothenate-cysteine ligase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539367, updated on 18-Sep-2024

Summary

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Official Symbol
ppc1
Official Full Name
phosphopantothenate-cysteine ligase
Primary source
PomBase:SPCC4B3.18
Locus tag
SPOM_SPCC4B3.18
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
cab2
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Genomic context

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See ppc1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1142616..1144233, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytochrome c oxidase biogenesis protein cmc2 Neighboring gene ubiquinol cytochrome-c reductase assembly protein Cbp3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA. Nakamura T, et al. Open Biol, 2012 Sep. PMID 23091701, Free PMC Article
  2. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
  3. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables phosphopantothenate--cysteine ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphopantothenate--cysteine ligase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process from pantothenate IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in coenzyme A biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in coenzyme A biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
phosphopantothenate-cysteine ligase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1142616..1144233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023064.3 → NP_588072.1  phosphopantothenate-cysteine ligase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588072.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9USK7
    Conserved Domains (2) summary
    COG0452
    Location:2 → 316
    CoaBC; Phosphopantothenoylcysteine synthetase/decarboxylase [Coenzyme transport and metabolism]
    cl04410
    Location:43 → 263
    DFP; DNA / pantothenate metabolizm flavoprotein
Nucleotide Protein
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