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sal3 karyopherin/importin beta family nuclear import signal receptor Sal3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539387, updated on 18-Sep-2024

Summary

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Official Symbol
sal3
Official Full Name
karyopherin/importin beta family nuclear import signal receptor Sal3
Primary source
PomBase:SPCC1840.03
Locus tag
SPOM_SPCC1840.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
pse1
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Genomic context

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See sal3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (2260016..2263761)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene metacaspase Pca1 Neighboring gene ncRNA Neighboring gene phosphoglucomutase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1. Park J, et al. Traffic, 2012 Apr. PMID 22268381
  2. The sal3(+) gene encodes an importin-beta implicated in the nuclear import of Cdc25 in Schizosaccharomyces pombe. Chua G, et al. Genetics, 2002 Oct. PMID 12399381, Free PMC Article
  3. Characterization of the nuclear import mechanism of the CCAAT-regulatory subunit Php4. Khan MG, et al. PLoS One, 2014. PMID 25330182, Free PMC Article
  4. The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries. Sha Z, et al. Mol Cell, 2009 Oct 9. PMID 19818717, Free PMC Article
  5. Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis. Chen XQ, et al. Yeast, 2004 Apr 30. PMID 15116432

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Further analysis by pull-down experiments revealed that Php4 is a cargo of the karyopherins Imp1, Cut15 and Sal3.
    Title: Characterization of the nuclear import mechanism of the CCAAT-regulatory subunit Php4.
  2. The karyopherin Sal3 is required for nuclear import of Rdp1
    Title: The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables nuclear import signal receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear import signal receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables nuclear import signal receptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein import into nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nuclear envelope HDA PubMed 
is_active_in nuclear periphery HDA PubMed 
is_active_in nuclear periphery IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
karyopherin/importin beta family nuclear import signal receptor Sal3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2260016..2263761
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023492.3 → NP_588502.1  karyopherin/importin beta family nuclear import signal receptor Sal3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588502.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74476, Q9US74
    Conserved Domains (4) summary
    cd00020
    Location:448 → 552
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam13513
    Location:385 → 439
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:374 → 478
    HEAT_2; HEAT repeats
    sd00044
    Location:376 → 397
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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