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saf1 splicing-associated factor Saf1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539395, updated on 18-Sep-2024

Summary

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Official Symbol
saf1
Official Full Name
splicing-associated factor Saf1
Primary source
PomBase:SPCC663.11
Locus tag
SPOM_SPCC663.11
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See saf1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1653848..1655582)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene dehydrogenase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA (uracil-O(2)-)-methyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene poly(A) polymerase Cid12 Neighboring gene NatA N-acetyltransferase subunit Naa50

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Splicing of branchpoint-distant exons is promoted by Cactin, Tls1 and the ubiquitin-fold-activated Sde2. Anil AT, et al. Nucleic Acids Res, 2022 Sep 23. PMID 36095128, Free PMC Article
  2. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Buttrick GJ, et al. Mol Biol Cell, 2011 Dec. PMID 21965289, Free PMC Article
  3. A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast. Bayne EH, et al. Genome Biol, 2014. PMID 25274039, Free PMC Article
  4. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article
  5. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Ren L, et al. PLoS One, 2011 Feb 28. PMID 21386897, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA cis splicing, via spliceosome IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of U2-type spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
splicing-associated factor Saf1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1653848..1655582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355928.2 → NP_001342746.1  splicing-associated factor Saf1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74517
    Conserved Domains (2) summary
    pfam09429
    Location:4 → 79
    Wbp11; WW domain binding protein 11
    pfam12622
    Location:115 → 157
    NpwBP; mRNA biogenesis factor
Nucleotide Protein
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