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tfx1 translin family protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539455, updated on 22-Jun-2024

Summary

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Gene symbol
tfx1
Gene description
translin family protein
Locus tag
SPOM_SPCC736.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPCC736.09c
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Genomic context

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See tfx1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (329570..330603, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor, CBF1/Su(H)/LAG-1 family Cbf11 Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein uS8m

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mapping of interaction sites of the Schizosaccharomyces pombe protein Translin with nucleic acids and proteins: a combined molecular genetics and bioinformatics study. Eliahoo E, et al. Nucleic Acids Res, 2010 May. PMID 20081200, Free PMC Article
  2. Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX. Jaendling A, et al. Biochim Biophys Acta, 2008 Feb. PMID 18062930
  3. Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX. Laufman O, et al. Nucleic Acids Res, 2005. PMID 16043634, Free PMC Article
  4. Biochemical characterization of clinically relevant mutations of human Translin. Pillai V, et al. Mol Cell Biochem, 2023 Apr. PMID 36098897
  5. Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe. Eliahoo E, et al. Biochim Biophys Acta, 2014 Apr. PMID 24382491

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TRAX is a non-essential protein that interacts with the translin protein. [trax]
    Title: Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA processing TAS
Traceable Author Statement
more info
 PubMed 
NOT involved_in double-strand break repair via homologous recombination TAS
Traceable Author Statement
more info
 PubMed 
NOT involved_in double-strand break repair via nonhomologous end joining TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
translin family protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    329570..330603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022773.3 → NP_587780.1  translin family protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587780.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74955
    Conserved Domains (1) summary
    COG2178
    Location:1 → 219
    COG2178; Predicted RNA- or ssDNA-binding protein, translin family [General function prediction only]
Nucleotide Protein
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