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vps35 retromer complex subunit Vps35 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539462, updated on 18-Sep-2024

Summary

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Official Symbol
vps35
Official Full Name
retromer complex subunit Vps35
Primary source
PomBase:SPCC777.13
Locus tag
SPOM_SPCC777.13
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See vps35 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003421.2 (1619366..1622409)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ER stress response thioredoxin family membrane disulfide oxidoreductase Neighboring gene mitochondrial ribosomal protein subunit L9 Neighboring gene ncRNA Neighboring gene protein Gta3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase Prp4 Neighboring gene tRNA dihydrouridine synthase Dus4 Neighboring gene protein phosphatase regulatory subunit Ekc1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased copper toxicity in Saccharomyces cerevisiae lacking VPS35, a component of the retromer and monogenic Parkinson disease gene in humans. Sowada N, et al. Biochem Biophys Res Commun, 2016 Aug 5. PMID 27262440
  2. Vacuolar protein sorting receptor in Schizosaccharomyces pombe. Iwaki T, et al. Microbiology (Reading), 2006 May. PMID 16622069
  3. Analysis of the SNARE Stx8 recycling reveals that the retromer-sorting motif has undergone evolutionary divergence. Yanguas F, et al. PLoS Genet, 2021 Mar. PMID 33788833, Free PMC Article
  4. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article
  5. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in endosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of retromer complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of retromer complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of retromer, cargo-selective complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
retromer complex subunit Vps35

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1619366..1622409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023250.3 → NP_588260.2  retromer complex subunit Vps35 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74552, P78830
    Conserved Domains (1) summary
    pfam03635
    Location:14 → 775
    Vps35; Vacuolar protein sorting-associated protein 35
Nucleotide Protein
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