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psk1 serine/threonine protein kinase S6K family Psk1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539494, updated on 18-Sep-2024

Summary

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Official Symbol
psk1
Official Full Name
serine/threonine protein kinase S6K family Psk1
Primary source
PomBase:SPCC4G3.08
Locus tag
SPOM_SPCC4G3.08
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See psk1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (457709..459495, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA repair protein Rhp42 Neighboring gene ncRNA Neighboring gene GTPase-activating protein Gyp3 Neighboring gene ncRNA Neighboring gene PHD finger domain-containing protein Phf1 Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL29m

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast TOR complex 1 phosphorylates Psk1 through an evolutionarily conserved interaction mediated by the TOS motif. Morozumi Y, et al. J Cell Sci, 2021 Oct 1. PMID 34499159, Free PMC Article
  2. Multiple crosstalk between TOR and the cell integrity MAPK signaling pathway in fission yeast. Madrid M, et al. Sci Rep, 2016 Nov 23. PMID 27876895, Free PMC Article
  3. Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinase. Nakashima A, et al. J Cell Sci, 2012 Dec 1. PMID 22976295, Free PMC Article
  4. Global coordination of transcriptional control and mRNA decay during cellular differentiation. Amorim MJ, et al. Mol Syst Biol, 2010 Jun 8. PMID 20531409, Free PMC Article
  5. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results provide convincing evidence that /Psk1/Rps6 constitutes a nutrient-dependent signaling pathway in fission yeast.
    Title: Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinase.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosomal protein S6 kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables signaling adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in TORC1 signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in TORC1 signaling IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in positive regulation of cytoplasmic translation EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine/threonine protein kinase S6K family Psk1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    457709..459495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022823.3 → NP_587830.1  serine/threonine protein kinase S6K family Psk1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587830.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O00044, Q12706
    Conserved Domains (3) summary
    smart00133
    Location:351 → 418
    S_TK_X; Extension to Ser/Thr-type protein kinases
    smart00220
    Location:91 → 335
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05123
    Location:97 → 350
    STKc_AGC; Catalytic domain of AGC family Serine/Threonine Kinases
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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