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uap2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539783, updated on 11-Sep-2024

Summary

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Official Symbol
uap2
Primary source
PomBase:SPBC1289.02c
Locus tag
SPOM_SPBC1289.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (4384037..4385590, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Nop16 Neighboring gene SEL1/TPR repeat protein1, 3-beta-glucan synthase regulatory factor Chf3/Chr4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ran GTPase Spi1 Neighboring gene Boi family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular characterization of a novel fission yeast gene spUAP2 that interacts with the splicing factor spU2AF59. McKinney R, et al. Curr Genet, 1997 Nov. PMID 9371883
  2. Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation. Ochotorena IL, et al. J Cell Sci, 2001 Aug. PMID 11686295
  3. Mutations in the large subunit of U2AF disrupt pre-mRNA splicing, cell cycle progression and nuclear structure. Beales M, et al. Yeast, 2000 Aug. PMID 10923022
  4. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of U2-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2-type spliceosomal complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
U2 snRNP-associated protein Uap2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    4384037..4385590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023847.3 → NP_596826.1  U2 snRNP-associated protein Uap2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596826.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O43120
    Conserved Domains (3) summary
    COG0724
    Location:1 → 220
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12281
    Location:109 → 202
    RRM1_TatSF1_like; RNA recognition motif 1 in HIV Tat-specific factor 1 (Tat-SF1) and similar proteins
    cd12285
    Location:249 → 333
    RRM3_RBM39_like; RNA recognition motif 3 in vertebrate RNA-binding protein 39 (RBM39) and similar proteins
Nucleotide Protein
Heading Accession and Version

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