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rpb8 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539794, updated on 11-Sep-2024

Summary

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Official Symbol
rpb8
Primary source
PomBase:SPBC14C8.12
Locus tag
SPOM_SPBC14C8.12
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (2223646..2224720)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene mitochondrial 54S ribosomal protein bL28m Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SRR1 family protein, DNA-repair associated protein, Srr1, conflicting annotations across species Neighboring gene rRNA processing protein Pol5 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. [Structural-functional characteristics of the Schizosaccharomyces pombe rpb8+ gene, coding the subunit of RNA polymerase I-III, specific only for eukaryotes]. Shpakovskiĭ GV, et al. Bioorg Khim, 1998 Feb. PMID 10335407
  2. The Rpb4 subunit of fission yeast Schizosaccharomyces pombe RNA polymerase II is essential for cell viability and similar in structure to the corresponding subunits of higher eukaryotes. Sakurai H, et al. Mol Cell Biol, 1999 Nov. PMID 10523639, Free PMC Article
  3. Location of subunit-subunit contact sites on RNA polymerase II subunit 3 from the fission yeast Schizosaccharomyces pombe. Yasui K, et al. Biochemistry, 1998 Apr 21. PMID 9548938
  4. RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing. Djupedal I, et al. Genes Dev, 2005 Oct 1. PMID 16204182, Free PMC Article
  5. Two large subunits of the fission yeast RNA polymerase II provide platforms for the assembly of small subunits. Ishiguro A, et al. J Mol Biol, 1998 Jun 19. PMID 9642054

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to RNA polymerase I activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA polymerase II activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA polymerase III activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transcription by RNA polymerase II TAS
Traceable Author Statement
more info
 PubMed 
involved_in transcription by RNA polymerase III TAS
Traceable Author Statement
more info
 PubMed 
involved_in transcription elongation by RNA polymerase I EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase I complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase II, core complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase II, holoenzyme EXP
Inferred from Experiment
more info
 PubMed 
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase III complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
DNA-directed RNA polymerase subunit Rpb8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2223646..2224720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021823.3 → NP_595915.1  DNA-directed RNA polymerase subunit Rpb8 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595915.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13459, O13460, Q92399
    Conserved Domains (1) summary
    smart00658
    Location:3 → 125
    RPOL8c; RNA polymerase subunit 8
Nucleotide Protein
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