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rpt1 proteasome regulatory subunit Rpt1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539862, updated on 18-Sep-2024

Summary

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Official Symbol
rpt1
Official Full Name
proteasome regulatory subunit Rpt1
Primary source
PomBase:SPBC16C6.07c
Locus tag
SPOM_SPBC16C6.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rpt1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (4341623..4343380, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitochondrial translation initiation factor Neighboring gene ncRNA Neighboring gene vacuolar protein sorting receptor vps10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquinol-cytochrome-c reductase complex subunit 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rpn5 is a conserved proteasome subunit and required for proper proteasome localization and assembly. Yen HC, et al. J Biol Chem, 2003 Aug 15. PMID 12783882
  2. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Lasker K, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307589, Free PMC Article
  3. Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Bohn S, et al. Proc Natl Acad Sci U S A, 2010 Dec 7. PMID 21098295, Free PMC Article
  4. Suppressor screening reveals common kleisin-hinge interaction in condensin and cohesin, but different modes of regulation. Xu X, et al. Proc Natl Acad Sci U S A, 2019 May 28. PMID 31072933, Free PMC Article
  5. The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast. Seo HD, et al. J Biol Chem, 2017 Oct 13. PMID 28784663, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables ATP hydrolysis activity NAS
Non-traceable Author Statement
more info
  
enables proteasome-activating activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables proteasome-activating activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
part_of proteasome regulatory particle, base subcomplex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proteasome regulatory particle, base subcomplex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
proteasome regulatory subunit Rpt1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    4341623..4343380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023826.3 → NP_596805.1  proteasome regulatory subunit Rpt1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596805.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42931
    Conserved Domains (2) summary
    COG1222
    Location:22 → 434
    RPT1; ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones]
    pfam00004
    Location:216 → 349
    AAA; ATPase family associated with various cellular activities (AAA)
Nucleotide Protein
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