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tif452 translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539870, updated on 22-Jun-2024

Summary

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Gene symbol
tif452
Gene description
translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor
Locus tag
SPOM_SPBC1709.18
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC409.01
Old locus tag
SPBC1709.18
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Genomic context

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See tif452 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (1134394..1135619)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene peptide N-glycanase Neighboring gene mRNA processing protein Cft2 Neighboring gene aromatic ring-opening dioxygenase Neighboring gene ncRNA Neighboring gene putative folylpolyglutamate synthase Neighboring gene ncRNA Neighboring gene NifU-like protein nfu1 Neighboring gene MIS12/MIND complex Mis12 Neighboring gene protein Swi5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. eIF4E isoform 2 in Schizosaccharomyces pombe is a novel stress-response factor. Ptushkina M, et al. EMBO Rep, 2004 Mar. PMID 14968130, Free PMC Article
  2. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
  3. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA 7-methylguanosine cap binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translational initiation ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISO
Inferred from Sequence Orthology
more info
  
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
part_of eukaryotic translation initiation factor 4F complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1134394..1135619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021360.3 → NP_595451.1  translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595451.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74743, Q9UUB9
    Conserved Domains (1) summary
    COG5053
    Location:16 → 243
    CDC33; Translation initiation factor 4E (eIF-4E) [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version

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